Results 31 to 40 of about 100,194 (263)

Anti-inflammatory effects of yeast-derived vacuoles on LPS-induced murine macrophage activation

Microbiology Spectrum, 2023
Saccharomyces cerevisiae is a single-celled fungal microorganism. S. cerevisiae-derived vacuoles are closely related to mammalian lysosomes, which play a role in the degradation of macromolecules by various hydrolytic enzymes.
Su-Min Lee, Yang-Hoon Kim, Jiho Min
doaj   +1 more source

The influence of osmotic stress on the content of calcium ions in the red beet vacuoles and on the transport activity of tonoplast proton pumps [PDF]

Journal of Stress Physiology & Biochemistry, 2012
The contents of calcium ions in the isolated vacuoles and in intact red beets under the conditions of dormancy and osmotic stress was determined. It is demonstrated that the content of calcium ions in the red beet vacuoles not exposed to osmotic stress ...
Ozolina N.V., E.V. Kolesnikova, V.N. Nurminsky, I.S. Nesterkina, L.V. Dudareva, T.I. Lapteva, R.K. Salyaev   +6 more
doaj  

Vacuoles in Bryophytes: Properties, Biogenesis, and Evolution

Frontiers in Plant Science, 2022
Vacuoles are the most conspicuous organelles in plants for their indispensable functions in cell expansion, solute storage, water balance, etc. Extensive studies on angiosperms have revealed that a set of conserved core molecular machineries orchestrate ...
Hao-ran Liu, Chao Shen, Danial Hassani, Wan-qi Fang, Zhi-yi Wang, Yi Lu, Rui-liang Zhu, Qiong Zhao, Qiong Zhao   +8 more
doaj   +1 more source

Pseudomonas aeruginosa utilizes the type III secreted toxin ExoS to avoid acidified compartments within epithelial cells. [PDF]

PLoS ONE, 2013
Invasive Pseudomonas aeruginosa (PA) can enter epithelial cells wherein they mediate formation of plasma membrane bleb-niches for intracellular compartmentalization.
Susan R Heimer, David J Evans, Michael E Stern, Joseph T Barbieri, Timothy Yahr, Suzanne M J Fleiszig   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

VacQuant: a tool to quantify neurodegeneration and associated vacuolation in brain tissue

Fly
Neurodegenerative diseases are devastating conditions characterized by progressive cognitive decline with few available treatments. Neurodegeneration can be quantified in vertebrate and invertebrate models of disease by analysis of vacuolation – the ...
Kate L. Jordan, Colin D. Veal, Charalambos P. Kyriacou, Flaviano Giorgini   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Soil to plant transfer of cadmium☆

Oilseeds and fats, crops and lipids
In soil, cadmium (Cd) is mainly adsorbed onto organic matter and iron hydroxides. Due to the difference in transmembrane electrochemical potential, the hydrated ions (Cd2+) present in the soil solution at the nanomolar level penetrate root cells.
Sterckeman Thibault
doaj   +1 more source

The entry of unclosed autophagosomes into vacuoles and its physiological relevance.

PLoS Genetics, 2022
It is widely stated in the literature that closed mature autophagosomes (APs) fuse with lysosomes/vacuoles during macroautophagy/autophagy. Previously, we showed that unclosed APs accumulated as clusters outside vacuoles in Vps21/Rab5 and ESCRT mutants ...
Zulin Wu, Haiqian Xu, Pei Wang, Ling Liu, Juan Cai, Yun Chen, Xiaomin Zhao, Xia You, Junze Liu, Xiangrui Guo, Tingting Xie, Jiajie Feng, Fan Zhou, Rui Li, Zhiping Xie, Yanhong Xue, Chuanhai Fu, Yongheng Liang   +17 more
doaj   +1 more source