Results 131 to 140 of about 100,485 (295)

Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome presenting as aseptic pustular dermatosis: A rare clinical manifestation

open access: yes
Arthritis &Rheumatology, Accepted Article.
Peter Chen   +6 more
wiley   +1 more source

Autophagy‐Targeting Nanomedicine: Strike at the Heart of the Cancer via Precise Modulation of Autophagy

open access: yesExploration, EarlyView.
This review emphasizes the critical role of autophagy in cancer treatment, highlighting the development of autophagy‐targeting nanomedicines and their applications in combination therapies. It explores how nanoplatforms can effectively regulate autophagy, underscoring the potential of integrating autophagy modulation with other treatment strategies to ...
Zhouyi Sun   +10 more
wiley   +1 more source

Specifically Breaking Through the Injured Blood‐Brain Barrier With Tannic Acid‐Based Nanomedicine for Ischemic Stroke Ischemia Reperfusion Treatment

open access: yesExploration, EarlyView.
Protecting neuronal mitochondria by eliminating the mitochondrial ROS (mtROS) storm is crucial to abrogate the neuronal damage cascade of ischemic stroke ischemia reperfusion (ISIR), which is a long‐standing challenge in the field of ischemic stroke (IS).
Xiaojing Shi   +15 more
wiley   +1 more source

Macrophage Targeting Protects Nerve Structure and Improves Muscle Innervation in a Mouse Model of Charcot‐Marie‐Tooth 2J

open access: yesGlia, EarlyView.
Hemizygous P0T124M mice develop a late‐onset axonopathy at 18 months of age. Pharmacological macrophage targeting with PLX5622 prevents distal axon degeneration in P0T124M mutant mice and mitigates motor impairment. ABSTRACT In several previous studies, we have shown that macrophage targeting with the CSF‐1 receptor specific kinase (c‐FMS) inhibitor ...
Dennis Klein   +8 more
wiley   +1 more source

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