Results 111 to 120 of about 43,537 (271)
Microscopic colitis is associated with an increased risk of dementia in a Swedish population
Journal of Internal Medicine, Volume 299, Issue 2, Page 216-227, February 2026.Abstract Background The microbiota–gut–brain axis has been implicated in dementia. Yet whether dementia is associated with microscopic colitis (MC), an age‐related inflammatory colonic disease involving gut dysbiosis, remains unknown. Methods Using the nationwide ESPRESSO cohort in Sweden, we compared MC patients histologically diagnosed 1990–2017 and ...
Xiaoying Kang +4 more
wiley +1 more source
Back to Basics: A Curriculum to Address the Pediatric Cardiac Anesthesia Workforce Crisis
Pediatric Anesthesia, Volume 36, Issue 2, Page 122-127, February 2026.ABSTRACT The field of pediatric cardiac anesthesia faces a critical workforce shortage. Survival of children with congenital heart disease (CHD) has improved dramatically, increasing both lifetime procedural demand and case complexity. At the same time, the supply of fellowship‐trained pediatric cardiac anesthesiologists is shrinking due to an aging ...
Lindsey Loveland, Susan C. Nicolson
wiley +1 more source
Polisens självskydd : Vad används och vad kan förbättras?
, 2006 Vi har undersökt hur självskyddsinstruktörer ser på den självskyddsträning som bedrivs idag. Vi har bett dem berätta om vilka tekniker som de och andra poliser använder i tjänsten och jämfört detta med vad som lärs ut på polisutbildningar och polismyndigheter.
Westerberg, Johan, Zachrison, Jan
openaire +1 more source
Epigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, Volume 158, Issue 2, Page 423-432, 15 January 2026.Abstract In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.
Subhasree Kumar +2 more
wiley +1 more source
Advanced Science, Volume 13, Issue 4, 19 January 2026.LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui +16 more
wiley +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu +11 more
wiley +1 more source
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen +10 more
wiley +1 more source