Results 101 to 110 of about 218,284 (346)

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source

The Ventricular Assist Device team in the management of patients treated with long-term Mechanical Circulatory Support

Infermieristica Journal
The number of people with heart failure is increasing rapidly worldwide. Despite preventive measures, optimal medical therapy, and cardiac transplantation, the overall morbidity and mortality of this syndrome remain high.
Simone Amato, Andrea Battisti, Daniele Napolitano   +2 more
doaj   +1 more source

LKB1 Loss Sensitizes Lung Tumor Spheres to Mitomet‐Induced Ferroptosis, and These Effects are Enhanced by mTOR Inhibition

Molecular Carcinogenesis, EarlyView.
ABSTRACT Owing to their robust antioxidant defense mechanisms, cancer stem‐like cells (CSCs) maintain a low level of oxidative stress, which is crucial for preserving stemness and pluripotency. Therefore, agents that either directly generate reactive oxygen species (ROS) or inhibit the antioxidant defense systems can selectively induce oxidative cell ...
Xueqing Liang, Ali Nakhi, Peter I. Dosa, Gunda I. Georg, Fekadu Kassie   +4 more
wiley   +1 more source

Environmental and socio‐economic factors behind data provision in 17 citizen science projects

People and Nature, EarlyView.
Abstract Citizen science approaches in ecology have recently become increasingly popular. Although many advantages, such as the cost‐effective collection of vast amounts of data, outweigh the disadvantages, most projects face difficulties, such as non‐random sampling, pseudo‐absences or various biases, such as detection/reporting biases or participant ...
Zsóka Vásárhelyi, Barbara Barta, Marianna Biró, Zoltán Csabai, Gábor Földvári, Bálint Halpern, Zsófia Horváth, Erika Juhász, Balázs Károlyi, Kornélia Kurucz, Zsuzsanna Márton, László Mezőfi, Péter Lovászi, Barna Páll‐Gergely, Bálint Pernecker, Ádám Selmeczi‐Kovács, Zoltán Soltész, Éva Szabó, Ágnes Turóci, Vadonleső Group, Judit Vörös, László Zsolt Garamszegi   +21 more
wiley   +1 more source

Vad är omvårdnad och vad är det inte?

Sömn och Hälsa
I juni 2025 presenterade International Council of Nurses (ICN) en ny, uppdaterad definition av både nurse och nursing. Behovet av att definiera professionen är i sig inget nytt.
Pernilla Garmy
doaj   +1 more source

Pediatric Cardiac Function Staging and Management Recommendations

Pediatric Discovery, EarlyView.
ABSTRACT The global prevalence of heart failure in children continues to increase, accompanied by a growing disease burden. To advance early prevention and intervention by shifting the focus upstream in the disease process, the Cardiovascular Group of the Pediatrics Society of the Chinese Medical Association has introduced the concept of pediatric ...
Bo Pan, Ling Han, Jianxin Zhuang, Xing Shen, Chenggang Mao, Yao Lin, Jindou An, Huili Zhang, Chunhong Xie, Yanmin Zhang, Li Zhang, Ying Guo, Yanyan Xiao, Shiwei Yang, Lei Zhang, Yue Yuan, Ling Sun, Zhi Chen, Wenhong Ding, Yifei Li, Zipu Li, Jie Tian   +21 more
wiley   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source

Role of inflammatory cytokines and the gut microbiome in vascular dementia: insights from Mendelian randomization analysis

Frontiers in Microbiology
BackgroundBoth inflammatory cytokines and the gut microbiome are susceptibility factors for vascular dementia (VaD). The trends in the overall changes in the dynamics of inflammatory cytokines and in the composition of the gut microbiome are influenced ...
Yihan Yang, Ting Rao, Ting Rao, Sheng Wei, Jing Cheng, Ying Zhan, Teng Lin, Jincheng Chen, Jincheng Chen, Xiaoling Zhong, Yijing Jiang, Shanli Yang   +11 more
doaj   +1 more source

La materia

, 2023
Idealism and materialism, those two antagonistic visions of philosophy, are constantly perceived in architecture. Juan Gris said that a nail was made with the idea of a nail, while Braque thought that a nail was made with an iron.Thought and project ...
Espegel, Carmen
core  

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

The Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source