Results 81 to 90 of about 29,684 (188)
This study aims to evaluate the potential of a multistage pump design to enhance hemocompatibility in left ventricular assist devices. We found that the two‐stage concept offers favorable hemolysis measures compared to single‐stage designs, as the reduction in peak shear stresses outweighs the disadvantage associated with prolonged residence time ...
Sarah Linnemeier +6 more
wiley +1 more source
Bivalirudin burst dosing in children supported with paracorporeal ventricular assist devices: A single-center experience. [PDF]
Olsen BA +5 more
europepmc +1 more source
Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities
ABSTRACT Background Clinicians aspire to predict the emergence of Bipolar Disorder (BD) in a timely manner. To accomplish this, markers reflecting mental states that can be gathered non‐invasively and at large scale are needed. Here, we systematically evaluate evidence relating speech‐based markers to mood states in BD.
Farida Zaher +4 more
wiley +1 more source
Ousiometrics: The essence of meaning aligns with a power-danger-structure framework instead of valence-arousal-dominance. [PDF]
Dodds PS +9 more
europepmc +1 more source
Schematic illustration of the mechanisms by which the natural quassinoid brusatol induces apoptosis in myeloid leukemias and enhances venetoclax efficacy via p53‐dependent apoptosis and mitochondrial dysfunction. ABSTRACT While venetoclax‐based combinations have shown promising results in acute myeloid leukemia (AML), the remission duration is ...
Shin‐ichiro Kawaguchi +11 more
wiley +1 more source
Rethinking Vitamin A Deficiency: Its Causes, Ophthalmologic Presentation, and Management Gaps at a New England Tertiary Hospital. [PDF]
Fearon KH +4 more
europepmc +1 more source
ABSTRACT Background Low serum testosterone concentration has been reported to be causally linked to the risk of Type 2 diabetes (T2D). The benefit of T2D protection has been demonstrated to continue up to serum testosterone concentrations of 461 ng/dL (16 nmol/L).
Mahesh M. Umapathysivam +5 more
wiley +1 more source
Perilipin‐2‐Anchored Lipid Droplet‐Targeting Phototheranostics
This study reports two NIR theranostic dyes, C‐BDP‐OH and C‐BDP‐OMe. C‐BDP‐OMe targets lipid droplets via a dual‐anchoring mechanism with PLIN2, enabling wash‐free tumor imaging. With 62.6% photothermal conversion efficiency, it achieves tumor ablation by downregulating PLIN2, disrupting LD‐mitochondria crosstalk, and triggering apoptosis and ...
Lipeng Zhang +9 more
wiley +2 more sources
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump +10 more
wiley +1 more source
Altered microbial cargo in fecal microbiome-derived outer membrane vesicles as novel biomarkers for vascular dementia. [PDF]
Li X +8 more
europepmc +1 more source

