Results 81 to 90 of about 29,684 (188)

Comparison of a Miniaturized Implantable Two‐Stage Rotodynamic Blood Pump to Equivalent Single‐Stage Concepts

open access: yesArtificial Organs, Volume 50, Issue 8, Page 1125-1135, August 2026.
This study aims to evaluate the potential of a multistage pump design to enhance hemocompatibility in left ventricular assist devices. We found that the two‐stage concept offers favorable hemolysis measures compared to single‐stage designs, as the reduction in peak shear stresses outweighs the disadvantage associated with prolonged residence time ...
Sarah Linnemeier   +6 more
wiley   +1 more source

Speech and Language Markers of Bipolar Disorder: Challenges and Opportunities

open access: yesBipolar Disorders, Volume 28, Issue 5, August 2026.
ABSTRACT Background Clinicians aspire to predict the emergence of Bipolar Disorder (BD) in a timely manner. To accomplish this, markers reflecting mental states that can be gathered non‐invasively and at large scale are needed. Here, we systematically evaluate evidence relating speech‐based markers to mood states in BD.
Farida Zaher   +4 more
wiley   +1 more source

Ousiometrics: The essence of meaning aligns with a power-danger-structure framework instead of valence-arousal-dominance. [PDF]

open access: yesSci Adv
Dodds PS   +9 more
europepmc   +1 more source

The Natural Quassinoid Brusatol Enhances Venetoclax Efficacy and Overcomes Resistance in Myeloid Leukemias

open access: yesCancer Science, Volume 117, Issue 8, Page 2274-2288, August 2026.
Schematic illustration of the mechanisms by which the natural quassinoid brusatol induces apoptosis in myeloid leukemias and enhances venetoclax efficacy via p53‐dependent apoptosis and mitochondrial dysfunction. ABSTRACT While venetoclax‐based combinations have shown promising results in acute myeloid leukemia (AML), the remission duration is ...
Shin‐ichiro Kawaguchi   +11 more
wiley   +1 more source

Higher Serum Testosterone Protects Against the Development of Type 2 Diabetes in Middle‐Aged but Not Older Men

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6959-6964, August 2026.
ABSTRACT Background Low serum testosterone concentration has been reported to be causally linked to the risk of Type 2 diabetes (T2D). The benefit of T2D protection has been demonstrated to continue up to serum testosterone concentrations of 461 ng/dL (16 nmol/L).
Mahesh M. Umapathysivam   +5 more
wiley   +1 more source

Perilipin‐2‐Anchored Lipid Droplet‐Targeting Phototheranostics

open access: yesAngewandte Chemie, Volume 138, Issue 30, 20 July 2026.
This study reports two NIR theranostic dyes, C‐BDP‐OH and C‐BDP‐OMe. C‐BDP‐OMe targets lipid droplets via a dual‐anchoring mechanism with PLIN2, enabling wash‐free tumor imaging. With 62.6% photothermal conversion efficiency, it achieves tumor ablation by downregulating PLIN2, disrupting LD‐mitochondria crosstalk, and triggering apoptosis and ...
Lipeng Zhang   +9 more
wiley   +2 more sources

Opposing roles of DGAT‐mediated lipid droplet biogenesis in the regulation of ferroptosis sensitivity

open access: yesThe FEBS Journal, Volume 293, Issue 15, Page 4508-4532, August 2026.
Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump   +10 more
wiley   +1 more source

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