Results 61 to 70 of about 218,284 (346)

Effects of combinations of hypotaurine, Z-VAD-fmk, and trehalose on recovery rate and proliferation capacity of germ cells enriched for SSCs following cryopreservation.

open access: yes, 2016
(A) Percentage of viable cells recovered after thawing. (B) Proliferation potential of cells recovered after thawing. Control = basal freezing medium containing 10% DMSO and 10% FBS; H = basal freezing medium with hypotaurine (14 mM); Z = basal freezing ...
Seung-Jung Ha (3070140)   +7 more
core   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen   +7 more
wiley   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

open access: yesAdvanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu   +8 more
wiley   +1 more source

Microbial Colonization of the Cleft

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2013
Introduction: Surgical reconstruction of soft and hard tissues of the middle face and functional rehabilitation are keystones of the treatment of facial clefts.
W. Urbanová   +4 more
doaj   +1 more source

Effects of Z-VAD-FMK on cadmium-induced rPT cell apoptosis.

open access: yes, 2016
(a) Representative images of cleaved caspase-3 western blot after 12-h cadmium treatment in the absence or presence of Z-VAD-FMK. (b) Quantitative analysis of cleaved caspase-3; grayscale of the control was set at 1.
Xuezhong Liu (753908)   +11 more
core   +1 more source

Tumor Microenvironment‐Responsive Nanoreactor Induces Disulfidptosis in Pancreatic Cancer via Metabolic Interference and Redox Catalysis

open access: yesAdvanced Science, EarlyView.
Schematic illustration of a tumor microenvironment‐responsive nanoreactor for imaging‐guided induction of disulfidptosis in pancreatic cancer via metabolic interference and redox catalysis. (A) Stepwise fabrication of Pht@HMnO2‐HA, including MnO2 growth on a SiO2 template, template removal to form hollow mesoporous MnO2, Pht loading, and subsequent ...
Rui Fu   +10 more
wiley   +1 more source

Dementia etiology classification using NULISA plasma biomarkers and machine learning. [PDF]

open access: yesAlzheimers Dement
Abstract INTRODUCTION Accurate ante mortem differentiation among dementia etiologies remains challenging, particularly for atypical or mixed clinical presentations. Multiplexed plasma proteomics paired with supervised machine learning offers a minimally invasive and accessible approach for differential diagnosis.
DuBois KN   +9 more
europepmc   +2 more sources

BAHUSANSKRUTIK VAD

open access: yes, 2022
Sansruti ya sankalpanechya anek vyakhya aahet. Sankruti hi pravahi sankalpana aahe. yamadhe aata konatya shanka nahi. sanskruti shabdacha artha satatyane badalat asato.
openaire   +1 more source

Las oportunidades

open access: yes, 2021
Oportunidad es una palabra decididamente optimista, positiva, que nos remite a ese momento idóneo en el que todo es posible. Sin embargo, también presenta un lado oscuro al aliarse frecuentemente con el negativo concepto de crisis.
Beatriz Villanueva Cajide   +2 more
core  

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