Results 51 to 60 of about 311,841 (295)
, 2022 Sansruti ya sankalpanechya anek vyakhya aahet. Sankruti hi pravahi sankalpana aahe. yamadhe aata konatya shanka nahi. sanskruti shabdacha artha satatyane badalat asato.
openaire +1 more source
Advanced Science, EarlyView.IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu +10 more
wiley +1 more source
Preparación y Educación en el manejo de la Vía Aérea. Revisión 2015
Revista Electrónica de AnestesiaR, 1970 El propósito de la Educación Médica en cualquier campo, prepara al profesional para la adquisición de conocimientos, habilidades y profesionalidad necesaria para aportar un cuidado correcto al paciente.
Marisa Mariscal Flores +1 more
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Berlin Heart EXCOR en el periodo neonatal
Cirugía Cardiovascular, 2021 Resumen: El trasplante cardiaco es una terapia bien establecida para el tratamiento de la insuficiencia cardiaca terminal en pacientes pediátricos. Sin embargo, los niños pequeños presentan un mayor riesgo de muerte en lista de espera.
Carlos M. Merino +5 more
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Advanced Science, EarlyView.A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv +16 more
wiley +1 more source
Cirugía Cardiovascular, 2019 Durable ventricular assist devices (VAD), despite being a standard therapy for adults in end-stage heart failure, are not so extended among the paediatric population for some reasons.
Ana Redondo +4 more
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Advanced Science, EarlyView.ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu +10 more
wiley +1 more source
3D FACIAL MORPHOMETRY IN PATIENS WITH OCULO-AURICULO-VERTEBRAL SPECTRUM
Česká Stomatologie a Praktické Zubní Lékařství, 2019 Introduction and aim: Oculo-auriculo-vertebral spectrum (OAVS) is a congenital complex of extremely variable phenotypes. Typically, unilaterally affected structuresare facial structures developing from the first and second branchial arches and first ...
P. Švihlíková Poláčková +2 more
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Advanced Science, EarlyView.In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian +13 more
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Advanced Science, EarlyView.DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li +17 more
wiley +1 more source