Results 31 to 40 of about 31,199 (169)

Manejo de la vía aérea en un paciente con secuencia de Pierre Robin para la cirugía de distracción osteogénica mandibular

open access: yesRevista Electrónica de AnestesiaR, 2015
El síndrome o secuencia de Pierre Robin (SPR) es una rara afección genética con una incidencia de 1 por cada 8.500 recién nacidos, descrita en 1923 por Robin. Se caracteriza por la triada clásica de glosoptosis, obstrucción de la vía aérea y alteraciones
Rosana Guerrero Domínguez   +2 more
doaj   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

open access: yesAdvanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan   +12 more
wiley   +1 more source

¿Vía Aérea Difícil y Cirugía Ambulatoria…?

open access: yesRevista Electrónica de AnestesiaR, 2013
Esta revisión tiene como objetivos revisar 2 aspectos clave del manejo de la Vía Aérea Difícil (VAD) en cirugía ambulatoria. El proceso de selección de los pacientes con VAD conocida y el equipamiento que necesita el carro de VA para el manejo de una VAD
Briseida V Arrázola Cabrera   +3 more
doaj   +1 more source

An advanced universal circulatory assist device for left and right ventricular support: First report of an acute in vivo implantCentral MessagePerspective

open access: yesJTCVS Open, 2020
Background: The Advanced ventricular assist device (Advanced VAD) is designed as a universal pump intended to prevent backflow in the event of pump stoppage, to maintain physiological pulse pressure, and to be used as both a left and right VAD.
Takuma Miyamoto, MD, PhD   +6 more
doaj   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou   +8 more
wiley   +1 more source

Preparación y Educación en el manejo de la Vía Aérea. Revisión 2015

open access: yesRevista Electrónica de AnestesiaR, 1970
El propósito de la Educación Médica en cualquier campo, prepara al profesional para la adquisición de conocimientos, habilidades y profesionalidad necesaria para aportar un cuidado correcto al paciente.
Marisa Mariscal Flores   +1 more
doaj   +1 more source

Replenishment of vitamin A for 7 days partially restored hepatic gene expressions altered by its deficiency in rats

open access: yesFrontiers in Nutrition, 2022
We investigated the effects of vitamin A (VA) status on metabolism of Zucker rats with different genders and genotypes, and of short-term refeeding of a VA sufficient (VAS) diet on VA deficient (VAD) animals.
Yan Zhang, Kui Tian, Guoxun Chen
doaj   +1 more source

Elevated TRIM25 Impairs Poly (ADP‐ribose) Metabolism via PARG Degradation and Mediates Compression‐Induced Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng   +9 more
wiley   +1 more source

Durable mechanical circulatory support in paediatric heart failure: The experience at Great Ormond Street Hospital

open access: yesCirugía Cardiovascular, 2019
Durable ventricular assist devices (VAD), despite being a standard therapy for adults in end-stage heart failure, are not so extended among the paediatric population for some reasons.
Ana Redondo   +4 more
doaj   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu   +9 more
wiley   +1 more source

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