Results 1 to 10 of about 293,285 (189)

A Novel Conserved Protein in Streptococcus agalactiae, BvaP, Is Important for Vaginal Colonization and Biofilm Formation

MSphere, 2022
Streptococcus agalactiae (group B streptococcus [GBS]) infections in neonates are often fatal and strongly associated with maternal GBS vaginal colonization. Here, we investigated the role of an uncharacterized protein, BvaP, in GBS vaginal colonization.
Laura Cook
exaly   +3 more sources

Group B Streptococcus CAMP Factor Does Not Contribute to Interactions with the Vaginal Epithelium and Is Dispensable for Vaginal Colonization in Mice

Microbiology Spectrum, 2021
The Gram-positive pathogen group B Streptococcus (GBS) is a leading cause of neonatal bacterial infections, preterm birth, and stillbirth. Although maternal GBS vaginal colonization is a risk factor for GBS-associated adverse birth outcomes, mechanisms ...
Vicki Mercado-Evans, Jacob Zulk, Kathryn Patras   +2 more
exaly   +3 more sources

Interrelated Effects of Zinc Deficiency and the Microbiome on Group B Streptococcal Vaginal Colonization

MSphere, 2022
Group B Streptococcus (GBS) in the vaginal tract is a risk factor for preterm birth and adverse pregnancy outcomes. GBS colonization is also transient in nature, which likely reflects the contributions of pathogen determinants, interactions with ...
Jessica Metcalf, Lindsey Burcham, Kelly Doran   +2 more
exaly   +3 more sources

Serotype-specific acquisition and loss of group B streptococcus recto-vaginal colonization in late pregnancy. [PDF]

PLoS ONE, 2014
Maternal recto-vaginal colonization with Group B Streptococcus (GBS) and consequent vertical transmission to the newborn predisposes neonates to early-onset invasive GBS disease. This study aimed to determine the acquisition and loss of serotype-specific
Gaurav Kwatra, Peter V Adrian, Tinevimbo Shiri, Eckhart J Buchmann, Clare L Cutland, Shabir A Madhi   +5 more
doaj   +3 more sources

Genomic Analyses Identify Manganese Homeostasis as a Driver of Group B Streptococcal Vaginal Colonization

MBio, 2022
Group B Streptococcus (GBS) is associated with severe infections in utero and in newborn populations, including pneumonia, sepsis, and meningitis. GBS vaginal colonization of the pregnant mother is an important prerequisite for transmission to the ...
Ashton Belew, Najib M El-Sayed, Thomas Kehl-Fie   +2 more
exaly   +3 more sources

Protective Effect of Lactobacillus crispatus against Vaginal Colonization with Group B Streptococci in the Third Trimester of Pregnancy

Pathogens, 2022
Background: A normal vaginal microbiota may protect the vaginal mucosa from colonization by potentially pathogenic bacteria, including group B streptococci (GBS).
Maja Starc, Miha Lučovnik, Petra Eržen Vrlič, Samo Jeverica   +3 more
doaj   +1 more source

Maternal Vaginal Ureaplasma spp. Colonization in Early Pregnancy Is Associated with Adverse Short- and Long-Term Outcome of Very Preterm Infants

Children, 2021
Vaginal colonization with Ureaplasma (U.) spp. has been shown to be associated with adverse pregnancy outcome; however, data on neonatal outcome are scarce. The aim of the study was to investigate whether maternal vaginal colonization with U. spp.
Judith Rittenschober-Böhm, Tanja Habermüller, Thomas Waldhoer, Renate Fuiko, Stefan M. Schulz, Birgit Pimpel, Katharina Goeral, Armin Witt, Angelika Berger, Karin Pichler   +9 more
doaj   +1 more source

Prevalence of vaginal microorganisms among pregnant women according to trimester and association with preterm birth [PDF]

Obstetrics & Gynecology Science, 2018
ObjectiveThe aim of this study was to investigate the prevalence of abnormal vaginal microorganisms in pregnant women according to trimester, and to determine whether the presence of abnormal vaginal colonization is associated with higher risk of ...
Kyung-A Son, Minji Kim, Yoo Min Kim, Soo Hyun Kim, Suk-Joo Choi, Soo-young Oh, Cheong-Rae Roh, Jong-Hwa Kim   +7 more
doaj   +1 more source

Vaginal-perianal or vaginal-perineal compared with vaginal-rectal culture-based screening for Group B Streptococci (GBS) colonization during the third trimester of pregnancy: a systematic review and meta-analysis

BMC Pregnancy and Childbirth, 2022
Background Screening for maternal anogenital Group B streptococci (GBS) colonization in pregnancy with initiation of intravenous intrapartum antibiotic prophylaxis as indicated has led to a significant reduction in the incidence of neonatal GBS infection.
Hugh C. G. Nadeau, Courtney Bisson, Xi Chen, Yan D. Zhao, Marvin Williams, Rodney K. Edwards   +5 more
doaj   +1 more source

Identification of Key Determinants of Staphylococcus aureus Vaginal Colonization

mBio, 2019
Staphylococcus aureus is an important pathogen responsible for nosocomial and community-acquired infections in humans, and methicillin-resistant S. aureus (MRSA) infections have continued to increase despite widespread preventative measures. S.
Liwen Deng, Katrin Schilcher, Lindsey R. Burcham, Jakub M. Kwiecinski, Paige M. Johnson, Steven R. Head, David E. Heinrichs, Alexander R. Horswill, Kelly S. Doran   +8 more
doaj   +1 more source