Results 61 to 70 of about 9,442,643 (366)

Host and Microbiome Interplay Shapes the Vaginal Microenvironment

Frontiers in Immunology, 2022
The female reproductive tract harbors a unique microbiome, especially the vagina. The human vaginal microbiome exhibits a low diversity and is dominated by Lactobacillus species, compared to the microbiome of other organs. The host and vaginal microbiome
Myoung Seung Kwon, Heung Kyu Lee
doaj   +1 more source

Vaginal microbiota and human papillomavirus infection among young Swedish women

npj Biofilms and Microbiomes, 2020
Human papillomavirus (HPV) infection is one of the most common sexually transmitted diseases. To define the HPV-associated microbial community among a high vaccination coverage population, we carried out a cross-sectional study with 345 young Swedish ...
Liqin Cheng, Johanna Norenhag, Yue O. O. Hu, N. Brusselaers, E. Fransson, Andreas Ährlund-Richter, Unnur Guðnadóttir, P. Angelidou, Yinghua Zha, Marica Hamsten, I. Schuppe-Koistinen, M. Olovsson, L. Engstrand, J. Du   +13 more
semanticscholar   +1 more source

Vaginal Microbicides: Detecting Toxicities in Vivo that Paradoxically Increase Pathogen Transmission [PDF]

, 2006
BACKGROUND: Microbicides must protect against STD pathogens without causing unacceptable toxic effects. Microbicides based on nonoxynol-9 (N9) and other detergents disrupt sperm, HSV and HIV membranes, and these agents are effective contraceptives.
Abusuwwa, Raed, Anderson, Deborah J., Cone, Richard A., Hoen, Timothy, Moench, Thomas R., Wong, XiXi   +5 more
core   +3 more sources

Vaginal Microbiota Is Stable throughout the Estrous Cycle in Arabian Mares

Animals, 2020
Simple Summary Knowing which bacteria dominate vaginal microbiota and its variation throughout the cycle is important to study how to prevent reproductive diseases.
M. Barba, R. Martínez-Boví, J. Quereda, M. L. Mocé, M. Plaza-Dávila, E. Jiménez-Trigos, Á. Gómez-Martín, Pedro González-Torres, Belén Carbonetto, E. García-Roselló   +9 more
semanticscholar   +1 more source

Host-vaginal microbiota interactions in the pathogenesis of bacterial vaginosis.

Current Opinion in Infectious Diseases, 2019
PURPOSE OF REVIEW The cause of bacterial vaginosis, the most common cause of vaginal discharge in women, remains controversial. We recently published an updated conceptual model on bacterial vaginosis pathogenesis, focusing on the roles of Gardnerella ...
C. Muzny, Paweł Łaniewski, J. Schwebke, M. Herbst-Kralovetz   +3 more
semanticscholar   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Water dispersible microbicidal cellulose acetate phthalate film [PDF]

, 2003
BACKGROUND: Cellulose acetate phthalate (CAP) has been used for several decades in the pharmaceutical industry for enteric film coating of oral tablets and capsules.
A Robert Neurath, A Stone, AC Gerbase, AJ Nahmias, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AR Neurath, AV Kabanov, B Kovacs, C Coggins, CV Uglea, D Quintanar-Guerrero, DL Jones, DS Jones, G Green, G Ramjee, GN Milligan, H Arwidsson, H Chakraborty, H Ibrahim, H.L.,Jr. Martin, IJ Rosenstein, J Liao, JA Rottingen, JM Mann, JR Dyer, K Stiasny, KA Gates, KH Manson, KR Tambweker, L Van Damme, M Over, M Ratterree, MK Stafford, Nathan Strick, P Sakellariou, PL Perine, R Duncan, R Rustomjee, RE Roddy, RJ Harwood, RN Fichorova, RN Fichorova, SD Holmberg, SJ Reynolds, SR Goskonda, T Gyotoku, T Kawamura, T Kietzke, T Vemba, V Baeyens, V Rosilio, Yun-Yao Li   +57 more
core   +2 more sources

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets

Advanced Science, EarlyView.
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu, Peng Peng, Yi‐Ning Wang, Mao‐Yang He, Shuang He, Chen‐Tao Jin, Liu Yang, Xi Wang, Jia‐Xi Zheng, Jie Gao, Cheng‐Ran Xu   +10 more
wiley   +1 more source

The association between lifestyle factors and the composition of the vaginal microbiota: a review

European Journal of Clinical Microbiology and Infectious Diseases
Purpose The vaginal microbiota offers valuable insights into women’s sexual health and the risk of developing sexually transmitted infections (STIs) and bacterial vaginosis.
M. Morsli, Elise Gimenez, Chloé Magnan, Florian Salipante, S. Huberlant, Vincent Letouzey, Jean-Philippe Lavigne   +6 more
semanticscholar   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

Advanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen, Xiaokang Ma, Longlin Zhang, Hao Li, Jichang Zheng, Shengru Wu, Ke Zuo, Yulong Yin, Jing Wang, Bie Tan   +9 more
wiley   +1 more source