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Host and Microbiome Interplay Shapes the Vaginal Microenvironment

open access: yesFrontiers in Immunology, 2022
The female reproductive tract harbors a unique microbiome, especially the vagina. The human vaginal microbiome exhibits a low diversity and is dominated by Lactobacillus species, compared to the microbiome of other organs. The host and vaginal microbiome
Heung Kyu Lee
exaly   +4 more sources

The Vaginal Microbiome in Health and Disease—What Role Do Common Intimate Hygiene Practices Play?

open access: yesMicroorganisms, 2023
The vaginal microbiome is a dynamic, sensitive microenvironment. The hallmark of a ‘healthy’ vaginal microbiome is currently believed to be one dominated by Lactobacillus spp., which acidifies the vaginal environment and help to protect against invading ...
Matthew Payne   +2 more
exaly   +4 more sources

Maternal Vaginal Microbiome Composition Does Not Affect Development of the Infant Gut Microbiome in Early Life

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
Birth mode has been implicated as a major factor influencing neonatal gut microbiome development, and it has been assumed that lack of exposure to the maternal vaginal microbiome is responsible for gut dysbiosis among caesarean-delivered infants ...
Zoë G Hodgson, Soren Gantt, Janet Lyons
exaly   +3 more sources

First-void urine and cervicovaginal brushes for vaginal microbiome profiling: a proof-of-concept study [PDF]

open access: yesMicrobiology Spectrum
The human vaginal microbiome is a cornerstone of female reproductive health, influencing susceptibility to vaginal conditions, pregnancy complications, and urogenital infections.
Maria Pinedo-Bardales   +12 more
doaj   +2 more sources

The role of the vaginal microbiome in pregnancy loss and preterm birth: a commentary [PDF]

open access: yesMaternal Health, Neonatology and Perinatology
Background Eubiosis or dysbiosis of the vaginal microbiome may influence the rate of pregnancy loss and preterm birth, the major cause of neonatal and perinatal mortality worldwide.
Ronald F. Lamont   +4 more
doaj   +2 more sources

Vaginal microbiome and recurrent pregnancy loss [PDF]

open access: yesInfection and Immunity
The joy of every mother is to survive a healthy pregnancy and give birth to a healthy baby. However, until today, many couples are finding it difficult to welcome a baby.
Xingxing Yuan   +3 more
doaj   +2 more sources

Species and strain sharing in the vaginal microbiome of mothers and their adult daughters

open access: yesCell Reports
Summary: The vaginal microbiome is key for women’s health. However, its establishment, interindividual variation and dynamics remain poorly understood. Here, we investigate bacterial relatedness at species and strain level in adult mother-daughter pairs ...
Maria Pinedo-Bardales   +14 more
doaj   +2 more sources

Longitudinal Profiling of the Macaque Vaginal Microbiome Reveals Similarities to Diverse Human Vaginal Communities

open access: yesmSystems, 2021
The vaginal microbiota plays an important role in women’s reproductive and urogenital health. It is now well accepted that a “healthy” vaginal microbiome is dominated by Lactobacillus species.
Nicholas S. Rhoades   +6 more
doaj   +3 more sources

Host-microbiome interactions in distinct subsets of preterm labor and birth

open access: yesiScience, 2023
Summary: Preterm birth, the leading cause of perinatal morbidity, often follows premature labor, a syndrome whose prevention remains a challenge. To better understand the relationship between premature labor and host-microbiome interactions, we conducted
Jose Galaz   +10 more
doaj   +1 more source

The Utility of Voided Urine Samples as a Proxy for the Vaginal Microbiome and for the Prediction of Bacterial Vaginosis

open access: yesInfectious Microbes & Diseases, 2022
. Recent work has shown that the vaginal microbiome exerts a strong impact on women's gynecological health. However, collection of vaginal specimens is invasive and requires previous clinical training or the involvement of a trained clinician.
Bin Zhu   +10 more
doaj   +1 more source

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