Results 101 to 110 of about 40,493 (241)

Vaginal microbiota and mucosal pharmacokinetics of tenofovir in healthy women using tenofovir and tenofovir/levonorgestrel vaginal rings.

PLoS ONE, 2019
Recent data support that the vaginal microbiota may alter mucosal pharmacokinetics (PK) of topically delivered microbicides. Our team developed an intravaginal ring (IVR) that delivers tenofovir (TFV) (8-10 mg/day) alone or with levonorgestrel (LNG) (20 ...
Andrea Ries Thurman, Jill L Schwartz, Jacques Ravel, Pawel Gajer, Mark A Marzinke, Nazita Yousefieh, Sharon M Anderson, Gustavo F Doncel   +7 more
doaj   +1 more source

The Role of Vaginal Oestrogen Therapy in Postmenopausal Women With Pelvic Organ Prolapse: Does It Have Any Impact on Perioperative Outcomes? A Systematic Review of Randomised Controlled Trials

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Pelvic organ prolapse (POP) affects up to 50% of postmenopausal women, negatively impacting sexual function and quality of life. While surgery remains the primary treatment, increasing attention has been given to perioperative vaginal oestrogen therapy and its potential impact on surgical outcomes.
Gilda Sicilia, Salvatore Giovanni Vitale, Maurizio Nicola D'Alterio, Stefania Saponara, Francesco Scicchitano, Anna Maria Fulghesu, Rossella E. Nappi, Stefano Angioni   +7 more
wiley   +1 more source

Microbiote vaginal et vaginose [Vaginal microbiota and vaginosis]

, 2022
The vaginal microbiota is essentially composed of bacteria of the Lactobacillus genus. These bacteria, by their presence, prevent vaginal contamination by other potentially aggressive germs. Disturbances of the microbiota lead to a pathological state called dysbiosis, one of the most frequent pathogenic aspects of which is bacterial vaginosis.
Surbone, A., Pache, B., Mathevet, P.
openaire   +1 more source

Molecular estimation of alteration in intestinal microbial composition in Hashimoto's thyroiditis patients [PDF]

, 2017
The gut microbiota has a crucial effect on human health and physiology. Hypothyroid Hashimoto’s thyroiditis (HT) is an autoimmune disorder manifested with environmental and genetic factors.
Guo, Hui, Hou, Yin Jian, Ishaq, Hafiz Muhammad, Ma, Chaofeng, Mohammad, Imran Shair, Naseem, Zahid, Shahzad, Muhammad, Shi, Peijie, Wu, Xiaokang, Xu, Jiru   +9 more
core   +2 more sources

Effects of Live and Heat‐Treated Bifidobacterium longum CECT 7347 in Adults With Allergic Rhinitis: A Randomised, Double‐Blind, Placebo‐Controlled Trial

Allergy, EarlyView.
This randomized, double‐blind, placebo‐controlled trial evaluated the effects of live probiotic and HT postbiotic B. longum CECT 7347 in adults with moderate–severe allergic rhinitis. Postbiotic supplementation for 8 weeks significantly reduced CSMS and dSS, exceeding the established CSMS MCID with a 33% greater improvement, when compared to placebo ...
Ana Cardoso, Malwina Naghibi, Eric Climent, Andrea Rodenes‐Gavidia, Araceli Lamelas, Laura Llobregat, Juan Martínez‐Blanch, Daniel Friedman, Vineetha Vijayakumar, Richard Day   +9 more
wiley   +1 more source

Effects of the sampling time on the vaginal microbiota in healthy pregnant women: a prospective observational studyAJOG Global Reports at a Glance

AJOG Global Reports
Background: Studies using 16S rRNA gene sequencing have extensively examined the vaginal microbiota changes of pregnant women. However, no study has examined these changes considering the time of day at which vaginal fluid samples were collected from ...
Hiroshi Mori, MD, Eiji Shibata, PhD, Emi Kondo, MD, Mitsumasa Saito, PhD, Kiyoshi Yoshino, PhD, Kazumasa Fukuda, PhD   +5 more
doaj   +1 more source

The dynamics of vaginal and rectal Lactobacillus spp. flora in subsequent trimesters of pregnancy in healthy Polish women, assessed using the Sanger sequencing method [PDF]

, 2018
Background Lactobacilli play an important role in maintaining vaginal health and protection against bacterial infections in the genital tract. The aim of this study is to show the dynamics of changes of the vaginal and rectal Lactobacillus flora during ...
Bodaszewska-Lubaś, Małgorzata, Brzychczy-Włoch, Monika, Bulanda, Małgorzata, Dobrut, Anna, Gosiewski, Tomasz, Ochońska, Dorota, Pabian, Wojciech   +6 more
core   +1 more source

Longitudinal Follow‐Up of Gut and Salivary Microbiota in Children With Food Protein‐Induced Enterocolitis Syndrome

Allergy, EarlyView.
This study aimed to compare both the gut and salivary microbiota over time between allergic and tolerant patients and matched controls. Allergic patients with food protein‐induced enterocolitis syndrome exhibited lower gut and salivary alpha‐diversities, several genus‐level differences, and higher acetate levels than controls.
Anais Lemoine, Karine Adel‐Patient, Nathalie Kapel, Camille Mayeur, Marie‐Noelle Rossignol, Aurelia Bruneau, Patrick Tounian, Muriel Thomas, Ioannis Nicolis   +8 more
wiley   +1 more source

Real‐world evaluation of a population‐based vaginal self‐sampling program for cervical cancer prevention in Region Skåne, Sweden

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Large‐scale HPV self‐sampling screening distributed 557 976 kits, resulting in 208 386 returned samples with 98% validity. HPV positivity was detected in 19% of participants, leading to clinical follow‐up. Biopsy confirmed 980 high‐grade cervical lesions and 32 cervical cancers.
Caroline Hellsten, Ola Forslund, Christer Borgfeldt   +2 more
wiley   +1 more source

The significance of Lactobacillus crispatus and L. vaginalis for vaginal health and the negative effect of recent sex: a cross-sectional descriptive study across groups of African women [PDF]

, 2015
Background: Women in sub-Saharan Africa are vulnerable to acquiring HIV infection and reproductive tract infections. Bacterial vaginosis (BV), a disruption of the vaginal microbiota, has been shown to be strongly associated with HIV infection.
Gilles F Ndayisaba, Hans Verstraelen, Janneke van de Wijgert, Joris Menten, Kishor Mandaliya, Liselotte Hardy, Mary Mwaura, null null, Piet Cools, Rita Verhelst, Sinead Delany-Moretlwe, Tania Crucitti, Vicky Jespers   +12 more
core   +2 more sources