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Three-dimensional printing technologies can be implemented for the fabrication of personalized vaginal rings (VRs) as an alternative approach to traditional manufacturing. Although several studies have demonstrated the potential of additive manufacturing,
Laura Andrade Junqueira +6 more
doaj +1 more source
Adolescent Experiences with the Vaginal Ring [PDF]
To understand racial/ethnic minority adolescent females' experiences with the vaginal ring.We conducted in-depth interviews with a clinic-based sample of 32 young women aged 15-24 years who had used the vaginal ring.Qualitative analysis using grounded theory revealed that adolescents undergo a multi-stage process when trying the ring and adopting ring ...
Laura B, Epstein +4 more
openaire +2 more sources
Characteristics of Women Enrolled into a Randomized Clinical Trial of Dapivirine Vaginal Ring for HIV-1 Prevention. [PDF]
Women in sub-Saharan Africa are a priority population for evaluation of new biomedical HIV-1 prevention strategies. Antiretroviral pre-exposure prophylaxis is a promising prevention approach; however, clinical trials among young women using daily or ...
Thesla Palanee-Phillips +20 more
doaj +1 more source
Steroids diffuse through polysiloxone at a constant rate, and steroids placed in the vagina rapidly pass through the vaginal epithelium into the circulation. Combining these principles led to the development of contraceptive vaginal rings (CVR) consisting of various progestins, with and without oestrogen, placed in flexible polysiloxone, doughnut ...
openaire +2 more sources
The progestagen releasing vaginal ring
The results of the Manchester study and its reinforcement from data from the multicenter study indicate that the ring is a well-tolerated delivery system for low-dose progestagens. The expulsion rate is low and vaginal tolerance satisfactory. The pregnancy rate and bleeding pattern is of the same order as oral low-dose progestagens. Indeed, there is
M, Elstein, I D, Nuttall
openaire +2 more sources
Vaginal formulations containing prebiotics and probiotics for treatment of bacterial vaginosis
Bacterial vaginosis (BV) is a common dysbiosis of the human vagina in which commensal vaginal lactobacilli are displaced by mixed pathogenic bacterial populations. Current treatments by antibiotics result in short- term cure but often lead to recurrence.
Caixuan Wang +3 more
doaj +1 more source
Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA [PDF]
peer reviewedTopical vaginal sustained delivery of siRNA presents a significant challenge due to the short residence time of formulations. Therefore, a drug delivery system capable to adhere to the vaginal mucosa is desirable, as it could allow a ...
Furst, Tania +7 more
core +1 more source
Biomarkers and biometric measures of adherence to use of ARV‐based vaginal rings
Introduction Poor adherence to product use has been observed in recent trials of antiretroviral (ARV)‐based oral and vaginal gel HIV prevention products, resulting in an inability to determine product efficacy.
Randy M Stalter +5 more
doaj +1 more source
Background Cryptorchidism in dogs is of clinical concern due to its association with development of Sertoli cell tumours, seminomas and spermatic cord torsion.
Dorcas Oyueley Kodie +4 more
doaj +1 more source
Multipurpose vaginal rings for HIV prevention and non-hormonal contraception
Vaginal rings releasing antiretrovirals - either alone or in combination with contraceptive progestins - are being developed for contraception and prevention of human immunodeficiency virus (HIV) transmission via vagina.
Xin Shen +4 more
doaj +1 more source

