Results 271 to 280 of about 83,408 (314)

Vagus nerve stimulation in Lennox–Gastaut syndrome: Twenty‐four‐month data and experience from the CORE‐VNS study

open access: yesEpilepsia, EarlyView.
Abstract Objective The drug‐resistant epilepsy associated with Lennox–Gastaut syndrome (LGS) has a long‐term effect on patients and is difficult to treat with conventional pharmacological and nonpharmacological therapies. Our objective is to demonstrate that adjunctive vagus nerve stimulation (VNS) can help manage the seizures associated with LGS ...
Paul Lyons   +8 more
wiley   +1 more source

A multicenter cohort study on the efficacy, retention, and tolerability of cenobamate in patients with developmental and epileptic encephalopathies

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate retention and treatment characteristics of cenobamate (CNB) in patients with developmental and epileptic encephalopathies (DEEs) in clinical practice. Methods This multicenter, retrospective cohort study recruited all patients with DEEs who started CNB treatment between October 2020 and April ...
Elisa Buhleier   +11 more
wiley   +1 more source

MRI of the brain is safe in patients implanted with the vagus nerve stimulator

open access: bronze, 2001
Selim R. Benbadis   +5 more
openalex   +1 more source

The cerebellum in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder   +4 more
wiley   +1 more source

Seizure outcomes following epilepsy surgery in pediatric and young adult patients with high‐grade brain tumors: Results from a European survey

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy surgery is a standard treatment for drug‐resistant epilepsy, resulting in seizure freedom in a significant number of cases. Although frequently performed for low‐grade brain tumors, it is rarely considered for high‐grade tumors, despite the impact of chronic epilepsy on quality of life and cognition.
Robert Lersch   +34 more
wiley   +1 more source

Treating heart failure by targeting the vagus nerve. [PDF]

open access: yesHeart Fail Rev
Gentile F   +7 more
europepmc   +1 more source

Long‐term safety and effectiveness of fenfluramine in children and adults with Dravet syndrome

open access: yesEpilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome. Abstract Objective We analyzed the long‐term safety and effectiveness of fenfluramine (FFA) in patients with Dravet syndrome (DS) in an open‐label extension (OLE) study after participating in randomized ...
Ingrid E. Scheffer   +15 more
wiley   +1 more source

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