Results 121 to 130 of about 45,261 (260)

G protein‐coupled receptor‐mediated autophagy in health and disease

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan, Zeynep Aslıhan Durer, Beki Kan   +2 more
wiley   +1 more source

Interplay between inflammatory reflex and energetic metabolism in endotoxaemia: A role for haem oxygenase 1?

British Journal of Pharmacology, EarlyView.
Inflammation is vital for defence against injury and infection, but excessive inflammation can lead to tissue damage and disease. The central nervous system (CNS) helps regulate immune responses through neuroendocrine pathways, such as the hypothalamic–pituitary–adrenal axis and the anti‐inflammatory reflex, which limit systemic inflammation.
Evelin C. Cárnio, Luiz G. S. Branco, Fernanda Brognara, Patrícia Passaglia, Roberta Foresti, Roberto Motterlini   +5 more
wiley   +1 more source

Right-sided vagus nerve stimulation: Worldwide collection and perspectives. [PDF]

Ann Clin Transl Neurol
Zanello M, Voges B, Chelvarajah R, Sen A, Petelin Gadže Ž, Penchet G, De Benedictis A, Fornaro R, Iwasaki M, Iijima K, Jiltsova E, Mrak G, Barrit S, Moiraghi A, Landi A, Neale M, Magdum S, Caire F, Godet B, Domenech P, Gaillard R, Guenot M, Labuschagne J, Rainha Campos A, Rooijakkers H, El Tahry R, Von Hertwig Fernandes De Oliveira T, Alvarez-Sala A, Torres CV, Vale F, Pallud J, Carron R.   +31 more
europepmc   +1 more source

Opioid receptors in cardiovascular function

British Journal of Pharmacology, EarlyView.
Opioid receptors are G protein‐coupled receptors expressed by various cells in the heart, including myocytes and nerve fibres, and play a crucial role in modulating cardiac function. These receptors influence neural transmission, heart rate and myocyte contractility, offering cardioprotection.
Venkatesh Katari, Kesha K. Dalal, Narendra Kondapalli, Sailaja Paruchuri, Charles K. Thodeti   +4 more
wiley   +1 more source

Two decades of vagus nerve stimulation for stroke: a bibliometric analysis. [PDF]

Front Neurol
Deng J, Yang Z, Wang QM, Lv ZG.
europepmc   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Transcutaneous Vagus Nerve Stimulation Enhances Probabilistic Learning. [PDF]

Psychophysiology
Çakır R, Büyükgüdük İ, Bilim P, Erdinç A, Veldhuizen MG.   +4 more
europepmc   +1 more source

Regenerating Locus Coeruleus‐Norepinephrine (LC‐NE) Function: A Novel Approach for Neurodegenerative Diseases

Cell Proliferation, EarlyView.
The regeneration of LC‐NE from pluripotent stem cells (PSCs) could significantly mitigate the progression of Neurodegenerative diseases and alleviate associated psychiatric disease symptoms, providing a new approach to the treatment of neurological diseases.
Yana Yang, Yunlong Tao
wiley   +1 more source

Auricular Vagus Nerve Stimulation for Gastrointestinal Disorders: Hope or Hype? [PDF]

United European Gastroenterol J
Keszthelyi D.
europepmc   +1 more source

Safety and effectiveness of stiripentol in patients with Dravet syndrome: A prospective, 3‐year, postmarketing surveillance study

Developmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16285 Abstract Aim To conduct a postmarketing surveillance study of patients with Dravet syndrome in Japan to investigate the safety and effectiveness of long‐term, real‐world, clinical use of stiripentol (STP).
Yuki Kitamura, Hiroaki Ohyabu, Tatsuo Miura, Naomi Takei‐Masuda, Daisuke Matsui, Yushi Inoue, Yoko Ohtsuka   +6 more
wiley   +1 more source