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Vagus nerve stimulation therapy
Drugs of Today, 2004Until recently, antiepileptic drugs and traditional epilepsy surgery were the two primary treatment options available to patients with epilepsy. Drug therapy, however, does not always control seizures and can be associated with negative side effects. Additionally, only a minority of patients are candidates for epilepsy surgery. Vagus nerve stimulation (
James E. Baumgartner, James W. Wheless
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, 2011 In a recent paper (Nei et al. 2006), vagus nerve stimulation was assessed in terms of efficacy and safety as compared to corpus callosotomy. Results showed that although corpus callosotomy was more effective for generalized tonic clonic seizures and for atonic seizures, the risks and complications excelled those of vagus nerve stimulation by a ...
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Vagus nerve stimulation for epilepsy
Practical Neurology, 2020Refractory epilepsy causes physical, psychological, psychiatric and social morbidities and carries an increased risk of premature mortality. Resective neurosurgery brings the possibility of long-term seizure remission in those with focal epilepsy, but is only suitable in approximately half of the patients who undergo presurgical evaluation,1 either ...
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Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part III
Headache: The Journal of Head and Face Pain, 2015Vagus nerve stimulation (VNS) is currently undergoing multiple trials to explore its potential for various clinical disorders. To date, VNS has been approved for the treatment of refractory epilepsy and depression. It exerts antiepileptic or antiepileptogenic effect possibly through neuromodulation of certain monoamine pathways. Beyond epilepsy, VNS is
Hsiangkuo Yuan, Stephen D. Silberstein
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The chemical neuroanatomy of vagus nerve stimulation
Journal of Chemical Neuroanatomy, 2011In this short overview a reappraisal of the anatomical connections of vagal afferents is reported. The manuscript moves from classic neuroanatomy to review details of vagus nerve anatomy which are now becoming more and more relevant for clinical outcomes (i.e. the therapeutic use of vagus nerve stimulation).
RUFFOLI, RICCARDO +5 more
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2015
Vagus nerve stimulation (VNS) therapy is used for halting those seizures of medically refractory epilepsy patients in which therapy by antiepileptic drugs (AEDs) has failed to provide any reasonable comfort. Another disease which can be treated by VNS is chronic or recurrent depression in adult patients that is unmanageable by antidepressant drugs.
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Vagus nerve stimulation (VNS) therapy is used for halting those seizures of medically refractory epilepsy patients in which therapy by antiepileptic drugs (AEDs) has failed to provide any reasonable comfort. Another disease which can be treated by VNS is chronic or recurrent depression in adult patients that is unmanageable by antidepressant drugs.
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2001
Die Vagus-Nerv-Stimulation (VNS) stellt bei Patienten mit medikamentos therapierefraktarem Anfallsleiden und bei Patienten, die fur einen epilepsiechirurgischen Eingriff nicht in Frage kommen bzw. bei denen eine Operation keinen Erfolg erbrachte, eine mogliche therapeutische Option dar (Tabelle 18.1) (Fisher und Handforth 1999; Schmidt et al. 1999).
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Die Vagus-Nerv-Stimulation (VNS) stellt bei Patienten mit medikamentos therapierefraktarem Anfallsleiden und bei Patienten, die fur einen epilepsiechirurgischen Eingriff nicht in Frage kommen bzw. bei denen eine Operation keinen Erfolg erbrachte, eine mogliche therapeutische Option dar (Tabelle 18.1) (Fisher und Handforth 1999; Schmidt et al. 1999).
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Subpectoral Implantation of the Vagus Nerve Stimulator
Operative Neurosurgery, 2006AbstractObjective:To report the technique of subpectoral (SP) implantation of the vagus nerve stimulator (VNS) generator.Methods:We retrospectively reviewed and compared demographics and complications from patients receiving either subcutaneous (SQ; n = 107) or SP (n = 138) VNS implants, performed by one surgeon (WKD) between 1999 and 2003.
Orrin Devinsky +3 more
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Vagus Nerve Stimulation in the Developmentally Disabled
Epilepsy & Behavior, 2001Vagus nerve stimulation (VNS) with the neuro cybernetic prosthesis (NCP) is an approved treatment of partial seizures for patients 12 years and older. Developmentally disabled or mentally retarded patients with epilepsy may also benefit from VNS; however, their evaluation and management pose greater problems.
Susan A. Vitale, Mary R. Andriola
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Vagus-nerve stimulation for the treatment of epilepsy [PDF]
The Lancet Neurology, 2002 Vagus-nerve stimulation (VNS) is now an accepted treatment for patients with refractory epilepsy. There have been many studies suggesting that VNS affects the brain in such areas as the thalamus and other limbic structures. In addition, there is some evidence that norepinephrine is important in the prophylactic antiseizure effects of VNS.
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