Results 31 to 40 of about 30,177 (304)

Vagus nerve stimulation in cerebral stroke: biological mechanisms, therapeutic modalities, clinical applications, and future directions

Neural Regeneration Research
Stroke is a major disorder of the central nervous system that poses a serious threat to human life and quality of life. Many stroke victims are left with long-term neurological dysfunction, which adversely affects the well-being of the individual and the
Li Du, Xuan He, Xiaoxing Xiong, Xu Zhang, Zhihong Jian, Zhenxing Yang   +5 more
doaj   +1 more source

Vagus Nerve Visualization Using Fused Images of 3D-CT Angiography and MRI as Preoperative Evaluation for Vagus Nerve Stimulation

Brain Sciences, 2023
Vagus nerve stimulation (VNS) is an effective surgical option for intractable epilepsy. Although the surgical procedure is not so complicated, vagus nerve detection is sometimes difficult due to its anatomical variations, which may lead to surgical ...
Shunsuke Nakae, Masanobu Kumon, Akio Katagata, Kazuhiro Murayama, Yuichi Hirose   +4 more
doaj   +1 more source

Mortality and suicide risk in treatment-resistant depression: an observational study of the long-term impact of intervention.

PLoS ONE, 2012
Major depressive disorder is a common global disease that causes a significant societal burden. Most interventional studies of depression provide a limited assessment of the interventions on mortality and suicide risks.
Bryan Olin, Amara K Jayewardene, Mark Bunker, Francisco Moreno   +3 more
doaj   +1 more source

Non-invasive Auricular Vagus Nerve Stimulation as a Potential Treatment for Covid19-Originated Acute Respiratory Distress Syndrome

Frontiers in Physiology, 2020
Background: Covid-19 is an infectious disease caused by an invasion of the alveolar epithelial cells by coronavirus 19. The most severe outcome of the disease is the Acute Respiratory Distress Syndrome (ARDS) combined with hypoxemia and cardiovascular ...
Eugenijus Kaniusas, Eugenijus Kaniusas, Jozsef C. Szeles, Jozsef C. Szeles, Stefan Kampusch, Nuria Alfageme-Lopez, Daniela Yucuma-Conde, Xie Li, Julio Mayol, Julio Mayol, Julio Mayol, Christoph Neumayer, Christoph Neumayer, Michele Papa, Fivos Panetsos, Fivos Panetsos   +15 more
doaj   +1 more source

Vagus nerve stimulation for epilepsy

Rinsho Shinkeigaku, 2011
Vagus nerve stimulation is the first electrical stimulation therapy for epilepsy. While its clinical use was approved by the European Union in 1994 and by the United States in 1997, it was approved last year and coverage by public insurance started last July in Japan.
Kensuke Kawai, Nobuhito Saito, Kenichi Usami   +2 more
openaire   +4 more sources

Electrical stimulation of the vagus nerve protects against cerebral ischemic injury through an anti-infammatory mechanism

Neural Regeneration Research, 2015
Vagus nerve stimulation exerts protective effects against ischemic brain injury; however, the underlying mechanisms remain unclear. In this study, a rat model of focal cerebral ischemia was established using the occlusion method, and the right vagus ...
Yao-xian Xiang, Wen-xin Wang, Zhe Xue, Lei Zhu, Sheng-bao Wang, Zheng-hui Sun   +5 more
doaj   +1 more source

The Present and Future of Vagus Nerve Stimulation [PDF]

Journal of Korean Neurosurgical Society, 2019
Epilepsy is one of the major chronic neurological diseases affecting many patients. Resection surgery is the most effective therapy for medically intractable epilepsy, but it is not feasible in all patients. Vagus nerve stimulation (VNS) is an adjunctive neuromodulation therapy that was approved in 1997 for the alleviation of seizures; however, efforts
Jeyul Yang, Ji Hoon Phi
openaire   +3 more sources

Sympathetic components in left and right human cervical vagus nerve: implications for vagus nerve stimulation

Frontiers in Neuroanatomy, 2023
Cervical vagus nerve stimulation is in a great variety of clinical situations indicated as a form of treatment. It is textbook knowledge that at the cervical level the vagus nerve contains many different fiber classes. Yet, recently, several reports have
Tom J. H. Ruigrok, Sophia A. Mantel, Sophia A. Mantel, Lara Orlandini, Lara Orlandini, Corné de Knegt, Corné de Knegt, Arnaud J. P. E. Vincent, Jochem K. H. Spoor   +8 more
doaj   +1 more source

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

Advanced Healthcare Materials, EarlyView.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin, Jose Crugeiras, Chiara Bisquoli, Davide Barboni, Martina Catani, Bruno Rodríguez‐Meana, Rita Boaretto, Michele Albicini, Stefano Caramori, Claudio Trapella, Thomas Stieglitz, Yara Baslan, Hanna Karlsson‐Fernberg, Fernanda L. Narvaez‐Chicaiza, Edoardo Marchini, Alberto Cavazzini, Ruben López‐Vales, Maria Asplund, Xavier Navarro, Stefano Carli   +19 more
wiley   +1 more source

Vagus Nerve Stimulation for Seizures

Archives of Medical Research, 2000
It is agreed that 1% of the general population is afflicted with epilepsy and close to 30% of epilepsy patients are intractable to medications. In spite of a recent increase in the number of new medications that are available on the market, many patients continue to have seizures or their seizures are controlled at the expense of intolerable side ...
Department of Neurology and Neuroscience, University of Florida, and College of Medicine and Malcolm Randall Veterans Administration Medical Center (VAMC), Gainesville, FL, USA ( host institution ), Uthman, Basim M   +1 more
openaire   +4 more sources