Results 11 to 20 of about 2,181 (130)

Pharmacokinetics of valaciclovir [PDF]

Journal of Antimicrobial Chemotherapy, 2004
While active against Herpesviridae, oral aciclovir is limited by low and inconsistent bioavailability. Modification of aciclovir by valine esterification, producing valaciclovir, results in significant increases in systemic aciclovir plasma levels.
Conan, MacDougall, B Joseph, Guglielmo
openaire   +2 more sources

A UHPLC–MS/MS Method for Therapeutic Drug Monitoring of Aciclovir and Ganciclovir in Plasma and Dried Plasma Spots

Biomedicines, 2021
The role of therapeutic drug monitoring (TDM) of valaciclovir (VA)/aciclovir (A) and valganciclovir/ganciclovir (VG/G) in critically ill patients is still a matter of debate.
Federica Pigliasco, Alessia Cafaro, Raffaele Simeoli, Sebastiano Barco, Alberto Magnasco, Maura Faraci, Gino Tripodi, Bianca Maria Goffredo, Giuliana Cangemi   +8 more
doaj   +1 more source

Genital herpes: modern views and prospects for the treatment [PDF]

Гинекология, 2020
The review focuses on the clinical and epidemiological characteristics of herpes viral infection, in particular genital herpes. The current treatment options for recurrent genital herpes are presented. A detailed description of valaciclovir is given.
Aleksey A. Khryanin, German Yu. Knorring
doaj   +1 more source

Features of genital herpes in women [PDF]

Гинекология, 2018
The paper presents a modern view of the current and the clinic of herpetic infection among women. The clinical manifestations and character of the course of atypical forms of herpes are described.
E V Dvoriankova, L R Sakaniia, O R Babaev, V V Shakhzadov, I M Korsunskaia   +4 more
doaj   +1 more source

Contribution of Serum Cytomegalovirus PCR to Diagnosis of Early CMV Primary Infection in Pregnant Women

Viruses, 2022
(1) Background: What is the role of serum CMV PCR in the diagnosis of recent primary infection (PI) in pregnant women when IgG avidity is uninformative? (2) Methods: Retrospective cohort study to compare serum versus whole blood CMV PCR.
Claire Périllaud-Dubois, Elise Bouthry, Lina Mouna, Christine Pirin, Corinne Vieux-Combe, Olivier Picone, Anne-Marie Roque-Afonso, Alexandre J. Vivanti, Christelle Vauloup-Fellous   +8 more
doaj   +1 more source

Efficacy of valaciclovir in preventing herpes zoster in patients receiving anifrolumab [PDF]

RMD Open
Zahir Amoura, Nathalie Costedoat-Chalumeau, Christophe Richez, Alexis Mathian, Didier Bessis, Marc André, Perrine Smets, Stanislas Faguer, Laurent Sailler, Bruno Pereira, François Chasset, Marc Scherlinger, Marie Jachiet, Estibaliz Lazaro, Julien Henry, Kevin Chevalier, Gaelle Richard-Colmant, Noemie Abisror, Jean-David Bouaziz, Nicole Ferreira-Maldent, Aurélia Lanteri, Ludovic Trefond, Claire Cazalets, Pierre-Yves Jeandel, Jerome Hadjadj, Nassim Ait Abdallah, Nicolas Belhomme, Alexandra Audemard, Thomas Moulinet, Julien Campagne, Thomas Barba, Sarah Lechtman, Cristina Livideanu, Sandrine Roque, Ruben Monteiro, Jeanne de La Rochefoucauld, Cecile Lesort, Diane Kottler, Cecile Saint-Pastou Terrier, Chloé Grolleau   +39 more
doaj   +2 more sources

Nécrose rétinienne aigue traitée par valaciclovir orale chez une patiente atteinte du Sida

PAMJ Clinical Medicine, 2020
La nécrose rétinienne aigue (ARN) est une affection uvéitique rare, observée classiquement chez les sujets immunocompétents et plus rarement chez les immunodéprimés, notamment infectés par le VIH.
El Houssaine Ait Lhaj, Salaheddine Bouabbadi, Youssef Bennouk, Mohammed Kriet   +3 more
doaj   +1 more source

Rabdomiolisis asociada al tratamiento con valaciclovir

Galicia Clínica, 2012
La rabdomiolisis es un efecto secundario asociado a un buen número de fármacos, entre ellos los antivirales. Describimos un caso de rabdomiolisis secundaria a valaciclovir, efecto no descrito anteriormente en laliteratura, en un contexto clínico muy ...
Héctor Enríquez Gómez, Javier De La Fuente Aguado, Laura González Vázquez, María Soledad Rodríguez Pecci   +3 more
doaj   +1 more source

Basic principles of management of patients with genital herpes [PDF]

Гинекология, 2019
Background. Genital herpes is a chronic recurrent sexually transmitted viral disease. Recurrent genital herpes is a serious medical and psychosocial issue which significantly worsens patients’ quality of life.
Tatiana Yu Pestrikova, Elena A Yurasova, Igor V Yurasov, Anastasia V Kotelnikova   +3 more
doaj   +1 more source

Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. [PDF]

PLoS ONE, 2012
To identify interactions a nucleoside analog library (NAL) consisting of 45 FDA-approved nucleoside analogs was screened against 23 enzymes of the human nucleotide metabolism using a thermal shift assay. The method was validated with deoxycytidine kinase;
Louise Egeblad, Martin Welin, Susanne Flodin, Susanne Gräslund, Liya Wang, Jan Balzarini, Staffan Eriksson, Pär Nordlund   +7 more
doaj   +1 more source