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Possible role of hyperimmunoglobulin in reducing the risk of maternal–fetal transmission of cytomegalovirus in the valacyclovir era: a case series [PDF]
Archives of Gynecology and ObstetricsIntroduction Valacyclovir is the only treatment option during pregnancy which has been demonstrated to be effective within a randomized clinical trial for prevention of transplacental cytomegalovirus (CMV) transmission.
Anna Barbiero +12 more
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A Case Report of Valacyclovir-Associated Neurotoxicity [PDF]
MicroorganismsWe report the case of a 69-year-old Hispanic female with end-stage renal disease (ESRD) on hemodialysis and a complex medical history who presented with acute altered mental status shortly after initiating valacyclovir at a non-renally adjusted dose. The
Kim Hoang +3 more
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Valacyclovir-induced neurotoxicity and nephrotoxicity in an elderly patient with a history of nephrectomy: a case report [PDF]
BMC NephrologyBackground Valacyclovir is a prodrug of acyclovir, both of which are commonly used in the treatment of varicella zoster and herpes simplex viruses. Its mechanism as a guanosine analog antiviral inhibits DNA polymerase via chain termination.
Sondos Badran +5 more
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Complications and Antiviral Strategies in Herpes Zoster: A Retrospective Evaluation of 50 Patients Treated in a Secondary Care Setting [PDF]
Infection and Drug ResistanceTürkan Tüzün Department of Infectious Diseases and Clinical Microbiology, Pamukkale University Faculty of Medicine, Denizli, TurkeyCorrespondence: Türkan Tüzün, Department of Infectious Diseases and Clinical Microbiology, Pamukkale University Faculty of ...
Tüzün T
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Cytomegalovirus infection during pregnancy [PDF]
Obstetrics & Gynecology Science, 2023 Cytomegalovirus (CMV) infection during pregnancy is a global silent problem. Additionally, it is the leading cause of congenital infections, non-genetic sensorineural hearing loss, and neurodevelopmental delays in infants.
Harshitha Kallubhavi Choodinatha +5 more
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Frontiers in Medicine, 2022 Whether valacyclovir-associated neurotoxicity (VAN) occurs more frequently in patients with end-stage renal disease (ESRD) on dialysis is unknown. This is the first population-based study to examine the risk of VAN associated with ESRD patients on ...
Yi-Chun Wang +13 more
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Design, Formulation and Evaluation of Physicochemical Properties of Valacyclovir Effervescent Tablet [PDF]
Trends in Pharmaceutical Sciences, 2022 Valacyclovir (VA) displays antiviral activity against Herpes simplex virus (HSV) and Varicella zoster virus (VZV). The aim of this study was to design, formulate and evaluate the physicochemical properties of effervescent tablets containing VA in order ...
Somayeh Taymouri +2 more
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Annals of Clinical Microbiology and Antimicrobials, 2020 Background Cytomegalovirus infection is one of the most common complications after solid organ transplantation. There have been several classes of antiviral drugs for the prevention of cytomegalovirus infection, such as acyclovir, valacyclovir ...
Yu Zhang +4 more
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Korean Journal of Transplantation, 2020 Background : Cytomegalovirus (CMV) infection is a crucial infection in kidney transplant recipients (KTRs) despite advancements in diagnostic and treatment methods. There are still many controversies about the ways to prevent CMV infection.
Woo Yeong Park +5 more
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Microorganisms, 2023 Valacyclovir (VACV) was developed as a prodrug of the most common anti-herpetic drug Acyclovir (ACV), aiming to enhance its bioavailability. Nevertheless, prolonged VACV oral treatment may lead to the development of important side effects. Nanotechnology-
Monica Argenziano +7 more
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