Results 21 to 30 of about 3,765 (187)

A UHPLC–MS/MS Method for Therapeutic Drug Monitoring of Aciclovir and Ganciclovir in Plasma and Dried Plasma Spots

open access: yesBiomedicines, 2021
The role of therapeutic drug monitoring (TDM) of valaciclovir (VA)/aciclovir (A) and valganciclovir/ganciclovir (VG/G) in critically ill patients is still a matter of debate.
Federica Pigliasco   +8 more
doaj   +1 more source

Contribution of Serum Cytomegalovirus PCR to Diagnosis of Early CMV Primary Infection in Pregnant Women

open access: yesViruses, 2022
(1) Background: What is the role of serum CMV PCR in the diagnosis of recent primary infection (PI) in pregnant women when IgG avidity is uninformative? (2) Methods: Retrospective cohort study to compare serum versus whole blood CMV PCR.
Claire Périllaud-Dubois   +8 more
doaj   +1 more source

Basic principles of management of patients with genital herpes [PDF]

open access: yesГинекология, 2019
Background. Genital herpes is a chronic recurrent sexually transmitted viral disease. Recurrent genital herpes is a serious medical and psychosocial issue which significantly worsens patients’ quality of life.
Tatiana Yu Pestrikova   +3 more
doaj   +1 more source

Real World Management of Cytopenias and Infections in Patients With Myelofibrosis Treated With Ruxolitinib. [PDF]

open access: yesEJHaem
ABSTRACT Introduction Ruxolitinib was the first JAK2 inhibitor approved for the treatment of primary and secondary myelofibrosis. It is currently used worldwide as first‐line therapy for advanced disease (intermediate‐2 and high‐risk) and is effective in polycythaemia vera (PV) and essential thrombocythaemia (ET), but not funded for this indication in ...
Butler LA   +3 more
europepmc   +2 more sources

Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. [PDF]

open access: yesPLoS ONE, 2012
To identify interactions a nucleoside analog library (NAL) consisting of 45 FDA-approved nucleoside analogs was screened against 23 enzymes of the human nucleotide metabolism using a thermal shift assay. The method was validated with deoxycytidine kinase;
Louise Egeblad   +7 more
doaj   +1 more source

Nécrose rétinienne aigue traitée par valaciclovir orale chez une patiente atteinte du Sida

open access: yesPAMJ Clinical Medicine, 2020
La nécrose rétinienne aigue (ARN) est une affection uvéitique rare, observée classiquement chez les sujets immunocompétents et plus rarement chez les immunodéprimés, notamment infectés par le VIH.
El Houssaine Ait Lhaj   +3 more
doaj   +1 more source

Impact of early treatment with valaciclovir on vertical cytomegalovirus transmission

open access: yesJournal of Paediatrics and Child Health, 2023
Congenital cytomegalovirus (CMV) infection has significant morbidity, including sensorineural hearing loss, developmental delay and ophthalmic abnormalities.

semanticscholar   +1 more source

Neurotoxicidad por valaciclovir en un paciente con insuficiencia renal crónica, reporte de caso clínico

open access: yesRevista Medicina e Investigación Clínica Guayaquil, 2023
El valaciclovir, se utiliza para tratar infecciones herpéticas; en pacientes con insuficiencia renal, su eliminación se ve afectada, lo que puede llevar a manifestaciones de neurotoxicidad.
Tatiana Carolina Marcillo Pin   +3 more
semanticscholar   +1 more source

Current practices of management of maternal and congenital Cytomegalovirus infection during pregnancy after a maternal primary infection occurring in first trimester of pregnancy: Systematic review.

open access: yesPLoS ONE, 2021
IntroductionCongenital CMV infection is the first worldwide cause of congenital viral infection but systematic screening of pregnant women and newborns for CMV is still debated in many countries.ObjectivesThis systematic review aims to provide the state ...
Claire Périllaud-Dubois   +5 more
doaj   +1 more source

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