Results 121 to 130 of about 6,125,000 (281)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Airborne in situ vertical profiling of HDO / H₂¹⁶O in the subtropical troposphere during the MUSICA remote sensing validation campaign [PDF]

, 2015
Christoph Dyroff, S. Sanati, Emanuel Christner, Andreas Zahn, M. Balzer, H. Bouquet, J. Barry McManus, Yenny González, Matthias Schneider   +8 more
openalex   +1 more source

Validation of Water Vapor Vertical Distributions Retrieved from MAX-DOAS over Beijing, China [PDF]

, 2020
Hua Lin, Cheng Liu, Chengzhi Xing, Qihou Hu, Qianqian Hong, Haoran Liu, Qihua Li, Wei Tan, Xiangguang Ji, Zhuang Wang, Jianguo Liu   +10 more
openalex   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Evaluation of self‐collected nasal, urine, and saliva samples for molecular detection of SARS‐CoV‐2 using an EUA approved RT‐PCR assay and a laboratory developed LAMP SARS‐CoV‐2 test

Immunity, Inflammation and Disease
As the SARS‐CoV‐2 virus spread throughout the world, millions of positive cases of COVID‐19 were registered and, even though there are millions of people already vaccinated against SARS‐CoV‐2, a large part of the global population remains vulnerable to ...
Ana Purcell‐Wiltz, Fernando Tadeu Zamuner, Karem Caraballo, Lorena De Jesus, Yaima Miranda, Denise Ortiz, Amanda García Negrón, Andrea Cortés Ortiz, Adriana Baez, Josefina Romaguera, Ivonne Jiménez, Alberto Ortiz, Jorge Acevedo, Liliana Viera, David Sidransky, Rafael Guerrero‐Preston   +15 more
doaj   +1 more source

Absorption Enhancement of Coated Absorbing Aerosols: Validation of the Photo-Acoustic Technique for Measuring the Enhancement [PDF]

, 2009
D. A. Lack, Christopher D. Cappa, Eben S. Cross, P. Massoli, Adam T. Ahern, P. Davidovits, T. B. Onasch   +6 more
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging [PDF]

, 2014
Emmanuel Rios Velazquez, Frank Hoebers, Hugo J.W.L. Aerts, Michelle M. Rietbergen, Ruud H. Brakenhoff, C. René Leemans, Ernst‐Jan M. Speel, Jos Straetmans, Bernd Kremer, Philippe Lambin   +9 more
openalex   +1 more source

Development and Validation of a Chiral Liquid Chromatographic Assay for Enantiomeric Separation and Quantification of Verapamil in Rat Plasma: Stereoselective Pharmacokinetic Application [PDF]

, 2021
Mostafa Mohammed, Mohamed Hefnawy, Abdulrhman Al-Majed, Haitham AlRabiah, Nasser Algrain, Ahmad J. Obaidullah, Abdulmalik Saleh Alfawaz Altamimi, Yousef A. Bin Jardan, Abdullah M. Al‐Hossaini   +8 more
openalex   +1 more source