Results 101 to 110 of about 2,498,425 (263)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Evaluation of self‐collected nasal, urine, and saliva samples for molecular detection of SARS‐CoV‐2 using an EUA approved RT‐PCR assay and a laboratory developed LAMP SARS‐CoV‐2 test

Immunity, Inflammation and Disease
As the SARS‐CoV‐2 virus spread throughout the world, millions of positive cases of COVID‐19 were registered and, even though there are millions of people already vaccinated against SARS‐CoV‐2, a large part of the global population remains vulnerable to ...
Ana Purcell‐Wiltz, Fernando Tadeu Zamuner, Karem Caraballo, Lorena De Jesus, Yaima Miranda, Denise Ortiz, Amanda García Negrón, Andrea Cortés Ortiz, Adriana Baez, Josefina Romaguera, Ivonne Jiménez, Alberto Ortiz, Jorge Acevedo, Liliana Viera, David Sidransky, Rafael Guerrero‐Preston   +15 more
doaj   +1 more source

A Database of High-Resolution Meteorological Drought Comprehensive Index Across China for the 1951–2022 Period

Data
Drought events exacerbated by global climate change occur frequently in China. Currently, high-spatiotemporal-resolution gridded meteorological drought index datasets are generally available for single time scales (e.g., 30, 60, 90, and 150 days) and do ...
Xijia Zhou, Mingwei Zhang, Guicai Li, Yuanyuan Wang, Zhaodi Guo   +4 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Measuring the Validity of Clustering Validation Datasets

IEEE Transactions on Pattern Analysis and Machine Intelligence
Clustering techniques are often validated using benchmark datasets where class labels are used as ground-truth clusters. However, depending on the datasets, class labels may not align with the actual data clusters, and such misalignment hampers accurate validation.
Hyeon Jeon, Michaël Aupetit 0001, DongHwa Shin, Aeri Cho, Seokhyeon Park, Jinwook Seo   +5 more
openaire   +3 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Estimation of All-Sky Gridded Diurnal Near-Surface Air Temperatures at Regional Scale From FY-4B Measurements

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The near-surface air temperature (${{T}_{air}}$) is a principal variable describing energy exchange and water circulation between the land surface and the atmospheric environment. The estimation of ${{T}_{air}}$ by satellite land surface temperature (LST)
Ronghan Xu, Xin Wang, Yonghong Hu, Lin Chen, Suling Ren, Guangzhen Cao, Di Xian, Eston Ranson Mogha   +7 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source