Results 111 to 120 of about 1,471,677 (265)
Covid-19 cases prediction using SARIMAX Model by tuning hyperparameter through grid search cross-validation approach. [PDF]
Expert Syst, 2022 Sah S +3 more
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Validation of the NewGust approach [PDF]
, 2003 The gust events described in the IEC-standard are formulated as coherent gusts of an inherent deterministic character, whereas the gusts experienced in real situation are of a stochastic nature with a limited spatial extension. This conceptual differencemay cause substantial differences in the load patterns of a wind turbine when a gust event is ...
openaire
Long-Term Projections of Cancer Incidence and Mortality in Japan and Decomposition Analysis of Changes in Cancer Burden, 2020-2054: An Empirical Validation Approach. [PDF]
Cancers (Basel), 2022 Nguyen PT, Saito E, Katanoda K.
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
مدیریت بهره وریThe current research was conducted with the aim of designing and validating a model of organizational intimacy in remote working conditions. The research adopts a developmental direction and employs a sequential-exploratory two-stage mixed-methods design.
seyed ali ghoreyshian +3 more
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A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease. [PDF]
Autophagy, 2022 Ai R +4 more
europepmc +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Validačná terapia (Validation therapy. Nonpharmacological approach to dementic patient)
Ostium, 2009 There is behaviour change occuring to old people, most of all dementic ones. Validation method by N. Feil helps to communicate with those people. The method is respecting uniqueness and originality of every person and is focused on diagnostics and ...
Peter Tavel
doaj