Results 51 to 60 of about 1,361,904 (215)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

PROSPECTS FOR HARMONIZATION OF FORENSIC SCIENCE OPERATIONS IN EURASEC MEMBER STATES VIA IMPLEMENTATION OF QUALITY MANAGEMENT SYSTEMS

open access: yesТеория и практика судебной экспертизы, 2014
The paper discusses various issues associated with the way forensic operations arecarried out in EurAsEC member states, as well as the development of new forensictechnologies, and the need for a uniform methodological approach to the tackling offorensic ...
S. Smirnova, Zh. Bekzhanov
doaj  

Validação da Escala de Abordagens de Aprendizagem (EABAP) em uma amostra Brasileira Validation of the Learning Approach Scale (LAS) in a Brazilian sample

open access: yesPsicologia: Reflexão e Crítica, 2011
O presente estudo teve como objetivo validar a Escala de Abordagens de Aprendizagem (EABAP), construída para mensurar a dimensão Superficial e Profunda, em uma amostra brasileira.
Cristiano Mauro Assis Gomes   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Synthetic Tabular Data Validation: A Divergence-Based Approach

open access: yesIEEE Access
The ever-increasing use of generative models in various fields where tabular data is used highlights the need for robust and standardized validation metrics to assess the similarity between real and synthetic data.
Patricia A. Apellaniz   +4 more
doaj   +1 more source

Ideological systems and its validation: a neutrosophic approach [PDF]

open access: yesNeutrosophic Sets and Systems, 2015
Ideologies face two critical problems in the reality, the problem of commitment and the problem of validation. Commitment and validation are two separate phenomena, in spite of the near universal myth that the human is committed because his beliefs are ...
Josué Nescolarde-Selva   +1 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Probing smoking craving with a multidimensional approach: validation of the 12-item French-language version of the Questionnaire on Smoking Urges

open access: yesNeuropsychiatric Disease and Treatment, 2014
Vincent Dethier,1 Alexandre Heeren,1,2 Laurence Galanti,3 Pierre Philippot,1 Joël Billieux1 1Laboratory for Experimental Psychopathology, Psychological Science Research Institute, Université catholique de Louvain, Louvain-la-Neuve, Belgium ...
Dethier V   +4 more
doaj  

Validating CircaCP: a generic sleep–wake cycle detection algorithm for unlabelled actigraphy data

open access: yesRoyal Society Open Science
Sleep–wake (SW) cycle detection is a key step for extracting temporal sleep metrics from actigraphy. Various supervised learning algorithms have been developed, yet their generalizability from sensor to sensor or study to study is questionable.
Shanshan Chen, Xinxin Sun
doaj   +1 more source

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