Results 71 to 80 of about 3,609,753 (274)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Developing and Validating a Questionnaire for Assessing School Organizational Health from an Islamic Perspective [PDF]

open access: yesمسائل کاربردی تعلیم و تربیت اسلامی
Objective: This study aims to develop and validate a questionnaire for assessing the school organizational health from an Islamic perspective. Method: This study was conducted in two main stages employing a mixed-method approach.
Mohammad Hasan Pardakhtci   +2 more
doaj  

Patterns of information security postures for socio-technical systems and systems-of-systems [PDF]

open access: yes, 2012
This paper describes a proposal to develop patterns of security postures for computer based socio-technical systems and systems-of-systems.
Glisson, W., Renaud, K., Storer, T.
core  

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

PROSPECTS FOR HARMONIZATION OF FORENSIC SCIENCE OPERATIONS IN EURASEC MEMBER STATES VIA IMPLEMENTATION OF QUALITY MANAGEMENT SYSTEMS

open access: yesТеория и практика судебной экспертизы, 2014
The paper discusses various issues associated with the way forensic operations arecarried out in EurAsEC member states, as well as the development of new forensictechnologies, and the need for a uniform methodological approach to the tackling offorensic ...
S. Smirnova, Zh. Bekzhanov
doaj  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Synthetic Tabular Data Validation: A Divergence-Based Approach

open access: yesIEEE Access
The ever-increasing use of generative models in various fields where tabular data is used highlights the need for robust and standardized validation metrics to assess the similarity between real and synthetic data.
Patricia A. Apellaniz   +4 more
doaj   +1 more source

Ideological systems and its validation: a neutrosophic approach [PDF]

open access: yesNeutrosophic Sets and Systems, 2015
Ideologies face two critical problems in the reality, the problem of commitment and the problem of validation. Commitment and validation are two separate phenomena, in spite of the near universal myth that the human is committed because his beliefs are ...
Josué Nescolarde-Selva   +1 more
doaj  

Validation of the procedures [PDF]

open access: yes
Validation strategies are described for procedures aimed at improving the rotor blade design process through a multidisciplinary optimization approach.
Mantay, Wayne R.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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