Results 81 to 90 of about 1,471,677 (265)

Adaptation and validation study of the Indonesian version of the Global Psychotrauma Screen in an undergraduate student population

Comprehensive Psychiatry
Background: The high incidence of potentially traumatic events (PTEs) in Indonesia warrants early identification of those with probable trauma-related disorders in order to tailor prevention and intervention for trauma-related symptoms.
Indira Primasari, Chris M. Hoeboer, Anne Bakker, Miranda Olff   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Next generation validation for next generation risk assessment

Frontiers in Toxicology
Next generation risk assessment (NGRA) demands a fundamental transformation in how toxicological test methods are validated. Traditional validation approaches, designed for animal tests and mainly for simple in vitro methods, are increasingly inadequate ...
Karolina Kopańska, Karolina Kopańska, Thomas Hartung, Thomas Hartung, Thomas Hartung, Thomas Hartung   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Two-Step Validation Approach for Tools To Study the DNA Repair Enzyme SNM1A. [PDF]

Chembiochem, 2023
Fay EM, Newton A, Berney M, El-Sagheer AH, Brown T, McGouran JF.   +5 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Performance validation of deep-learning-based approach in stool examination

Parasites & Vectors
Background Human intestinal parasitic infections (IPI) pose a significant global health issue caused by parasitic helminths and protozoa, affecting around 3.5 billion people worldwide, with more than 200,000 deaths annually.
Kristal Dale Felimon Corpuz, Teera Kusolsuk, Benjamaporn Wongphan, Putza Chonsawat, Kaung Myat Naing, Siridech Boonsang, Veerayuth Kittichai, Chia-Kwung Fan, Santhad Chuwongin, Dorn Watthanakulpanich   +9 more
doaj   +1 more source

Multi-Analyte Method for Antibiotic Residue Determination in Honey Under EU Regulation 2021/808

Antibiotics
Background/Objectives: Antibiotic detection in honey is challenging due to the complexity of this product, the typically low levels of residues, and the absence of Maximum Residue Levels (MRLs) for beehive products.
Helena Rodrigues, Marta Leite, Maria Beatriz P. P. Oliveira, Andreia Freitas   +3 more
doaj   +1 more source

Approach Not Very Valid

Deutsches Ärzteblatt international, 2021
openaire   +3 more sources