Results 91 to 100 of about 48,587,327 (320)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Development and Validation of an Educational Tool on Hypodermoclysis for Palliative Care Professionals

Nursing Reports
Background/Objectives: Hypodermoclysis has gained increasing recognition as a safe, effective, and minimally invasive method for administering medication and fluids in palliative care.
Maria Vanessa Tomé Bandeira de Sousa, Carlos Laranjeira, José Mateus Pires, Isabela Melo Bonfim, Luís Carlos Carvalho Graça, Karla Maria Carneiro Rolim, Lara Anisia Menezes Bonates, Régia Christina Moura Barbosa Castro, Ana Fátima Carvalho Fernandes   +8 more
doaj   +1 more source

Tradução e validação do The five part questionnaire for identifying hypermobility para a língua portuguesa do Brasil Translation into Brazilian Portuguese and validation of the five-part questionnaire for identifying hypermobility

Revista Brasileira de Reumatologia, 2011
INTRODUÇÃO: A hipermobilidade articular (HA) é uma condição clínica hereditária em que há aumento da elasticidade articular em movimentos passivos. Na população em geral, a frequência varia entre 10% e 20%, podendo ser estimada por métodos específicos ...
Daniela Aparecida de Moraes, Carlos Alberto Baptista, José Alexandre Souza Crippa, Paulo Louzada-Junior   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Validation of back-calculation equations for juvenile bluefish (Pomatomus saltatrix) with the use of tetracycline-marked otoliths [PDF]

, 2007
In recent years, a decrease in the abundance of bluefish (Pomatomus saltatrix) has been observed (Fahay et al., 1999; Munch and Conover, 2000) that has led to increased interest in a better understanding the life history of the species.
Oliveira, Kenneth, Roemer, Marja E.
core  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Semantic and cultural equivalence of the Intergenerational Exchanges Attitude Scale (IEAS)

Revista Brasileira de Geriatria e Gerontologia
Introduction: Understanding the multidimensionality of attitudes originating from exchanges between different generations is fundamental for the establishment of intergenerational cooperation and the reduction of stereotypes and prejudices.
Roberta dos Santos Tarallo, Anita Liberalesso Neri, Meire Cachioni   +2 more
doaj   +1 more source

Evaluation of clinical prediction models (part 2): how to undertake an external validation study

British medical journal
External validation studies are an important but often neglected part of prediction model research. In this article, the second in a series on model evaluation, Riley and colleagues explain what an external validation study entails and describe the key ...
R. Riley, Lucinda Archer, K. Snell, J. Ensor, P. Dhiman, Glen P. Martin, Laura J. Bonnett, Gary S. Collins   +7 more
semanticscholar   +1 more source