Results 101 to 110 of about 4,984,553 (349)

Design of Anisotropic Diffusion Hardware Fiber Phantoms [PDF]

open access: yes, 2009
A gold standard for the validation of diffusion weighted magnetic resonance imaging (DW-MRI) in brain white matter (WM) is essential for clinical purposes but still not available.
Baete, Steven   +3 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

VALIDACIÓN DE LA CITOLOGIA CÉRVICO UTERINA CONVENCIONAL CON PRUEBA DE REFERENCIA HISTOPATOLÓGICA EN LA IDENTIFICACIÓN DE CÁNCER ESCAMOCELULAR INVASOR

open access: yesRevista Chilena de Obstetricia y Ginecología, 2006
Antecedentes: La citología cérvico uterina convencional (CCUC) es la prueba de tamizaje más empleada en la detección del cáncer de cuello uterino, sin embargo su calidad es discutida.
Ernesto García A   +5 more
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A verification library for multibody simulation software [PDF]

open access: yes
A multibody dynamics verification library, that maintains and manages test and validation data is proposed, based on RRC Robot arm and CASE backhoe validation and a comparitive study of DADS, DISCOS, and CONTOPS that are existing public domain and ...
Frisch, Harold P.   +2 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Validation of the Atopic Dermatitis Control Tool (ADCT) and a Comparison with the Recap of Atopic Eczema Questionnaire (RECAP)

open access: yesActa Dermato-Venereologica
The Atopic Dermatitis Control Tool (ADCT) has not been validated in the Dutch population, and comparisons with the Recap of atopic eczema (RECAP) questionnaire are still lacking.
Junfen Zhang   +5 more
doaj   +1 more source

Validation de l’échelle du sentiment d’efficacité des enseignants à l’égard de l’intégration des technologies de l’information et des communications en classe (SETIC)

open access: yesMesure et Évaluation en Éducation, 2002
Cet article présente les résultats d’une étude ayant pour but d’élaborer un instrument de mesure du sentiment d’efficacité des enseignants à l’endroit de l’intégration des technologies dans la classe et d’en vérifier la structure factorielle.
Marc Dussault   +3 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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