Results 41 to 50 of about 5,067,780 (299)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Common misconceptions about validation studies [PDF]

International Journal of Epidemiology, 2020
Abstract Information bias is common in epidemiology and can substantially diminish the validity of study results. Validation studies, in which an investigator compares the accuracy of a measure with a gold standard measure, are an important way to understand and mitigate this bias.
Matthew P, Fox, Timothy L, Lash, Lisa M, Bodnar   +2 more
openaire   +2 more sources

Validation of a Predictive Model for Survival in Patients With Advanced Cancer: Secondary Analysis of RTOG 9714. [PDF]

, 2011
BackgroundThe objective of this study was to validate a simple predictive model for survival of patients with advanced cancer.MethodsPrevious studies with training and validation datasets developed a model predicting survival of patients referred for ...
Bruner, Deborah Watkins, Chow, Edward, Demas, William, Hartsell, William, III, Ivker, Robert, James, Jennifer L, Konski, Andre, Roach, Mack, Scarantino, Charles W, Suh, John H   +10 more
core  

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Effectiveness evaluation of a serious game for dental lost wax casting training

BMC Medical Education
Background A serious game module called “D-Casting” was developed in the previous study. This study aimed to determine the effectiveness of the D-Casting module.
YiZhen Wang, Yi Li, ChaoYi Ma, WeiYi Zhang, ZiYa Yuan, Qian Zhu, XiaoHan Zhao, Jinlin Song, Sheng Yang, Ping Ji, MengWei Pang   +10 more
doaj   +1 more source

Perceived Fatality Prior to COVID-19 Infection in 13 Latin American Countries (FAT-LAT-COVID-19): Revalidation of a Shortened Scale

Frontiers in Psychiatry, 2022
IntroductionCOVID-19 has generated great repercussions for the population globally; millions of deaths have been reported worldwide. The idea of death is especially exacerbated when there are close to death experiences that remind us how close we are to ...
Christian R. Mejia, Telmo Raúl Aveiro-Róbalo, Telmo Raúl Aveiro-Róbalo, Luciana D. Garlisi-Torales, Luciana D. Garlisi-Torales, Renzo Felipe Carranza Esteban, Oscar Mamani-Benito, Martín A. Vilela-Estrada, Víctor Serna-Alarcón, Damary S. Jaramillo-Aguilar, Javiera L. Rojas-Roa   +10 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

New Methodology for Non-destructive Identification of Body Fluid for Forensic Purposes

Arab Journal of Forensic Sciences & Forensic Medicine
The purpose of this research study was to test and subsequently validate a method based on the identification of biological fluids by nondestructive analysis, attributing phenotypic characteristics to biological stains.
Eugenio, Francesco Mercante, Teresa Di Sarno Giusto   +2 more
doaj   +1 more source

Equimetrix Device: Criteria Based Validation and Reliability Analysis of the Center of Mass and Base of Support of a Human Postural Assessment System

Sensors, 2021
Human postural control is a fundamental ability for static and dynamic tasks, especially in hiper- and hipo-functional populations, such as the elderly. The Equimetrix is a clinical device developed to assess both the base of support (BoS) and the center
Pedro Fonseca, Manoela Sousa, Ricardo Sebastião, Márcio Goethel, Pierre Barralon, Igone Idigoras, Filipa Sousa, Leandro Machado, João Paulo Vilas-Boas   +8 more
doaj   +1 more source