Results 71 to 80 of about 577,511 (310)

Severity of temporomandibular disorders in women: validity and reliability of the Fonseca Anamnestic Index

open access: yesBrazilian Oral Research, 2014
The aim of this study was to assess the validity and reliability of the Fonseca Anamnestic Index (IAF), used to assess the severity of temporomandibular disorders, applied to Brazilian women. We used a probabilistic sampling design. The participants were
Juliana Alvares Duarte Bonini Campos   +3 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Concurrent validity and test–retest reliability of VALD ForceDecks' strength, balance, and movement assessment tests

open access: yes
Objectives To evaluate the concurrent validity and test–retest reliability of common movement, strength, and balance tests using portable uniaxial dual force plates. Design Repeated measures cross-sectional study.
Collings, TJ   +3 more
core   +1 more source

Evaluación de tecnologías diagnósticas: conceptos básicos en un estudio con muestreo transversal Assessing a diagnostic test: basic concepts in a study with naturalistic sampling

open access: yesRevista Colombiana de Obstetricia y Ginecología, 2007
Los estudios de evaluación de pruebas diagnósticas son un diseño científico que nos ayuda a determinar la validez y la reproducibilidad de los procedimientos que pueden ser usados en la práctica clínica por médicos y otros profesionales de salud. Este es
María Isabel Castro-Jiménez   +2 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

External Tests of Peer Review Validity Via Impact Measures

open access: yesFrontiers in Research Metrics and Analytics, 2018
Peer review is used commonly across science as a tool to evaluate the merit and potential impact of research projects and make funding recommendations. However, potential impact is likely to be difficult to assess ex-ante; some attempts have been made to
Stephen A. Gallo, Scott R. Glisson
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Estudo dinâmico da mortalidade por tuberculose no Estado de São Paulo, Brasil: uma abordagem bayesiana

open access: yesCadernos de Saúde Pública
Neste trabalho, utilizamos a técnica bayesiana de modelos lineares dinâmicos para estudar a dinâmica da mortalidade por tuberculose (TB) no Estado de São Paulo, Brasil.
James Dean Oliveira dos Santos Junior   +1 more
doaj  

Factor structure, internal consistency and reliability of the Posttraumatic Stress Disorder Checklist (PCL): an exploratory study Estrutura fatorial, consistência interna e confiabilidade do Posttraumatic Stress Disorder Checklist (PCL): um estudo exploratório

open access: yesTrends in Psychiatry and Psychotherapy, 2012
INTRODUCTION: Posttraumatic stress disorder (PTSD) is an anxiety disorder resulting from exposure to traumatic events. The Posttraumatic Stress Disorder Checklist (PCL) is a self-report measure largely used to evaluate the presence of PTSD. OBJECTIVE: To
Eduardo de Paula Lima   +2 more
doaj  

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