Matrix Type Influences the Levels of Soluble Immune Checkpoints. [PDF]
This study aimed to assess whether the quantification of soluble immune checkpoints (sICs) is comparable between serum and EDTA‐plasma samples. We quantified 17 sICs by a multiplex bead‐based assay in paired serum and plasma‐EDTA samples collected from a cohort of 38 healthy subjects.
Buia V +7 more
europepmc +2 more sources
Eligibility criteria for clinical trials in AL amyloidosis result in exclusion of nearly half of real-world patients. [PDF]
HemaSphere, Volume 10, Issue 2, February 2026.
Bellofiore C +17 more
europepmc +2 more sources
Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus. [PDF]
What's new? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Civita P +12 more
europepmc +2 more sources
Deep resequencing unveils novel SNPs, InDels, and large structural variants for the clonal fingerprinting of sweet orange [Citrus sinensis (L.) Osbeck]. [PDF]
Abstract The large phenotypic variability characterizing the sweet orange [Citrus sinensis (L.) Osbeck] germplasm arose from spontaneous somatic mutations and led to the diversification of major groups (common, acidless, Navel, and pigmented). Substantial divergence also occurred within each varietal group.
Scaglione D +11 more
europepmc +2 more sources
Stratification of Motor Cortex Excitability to Transcranial Stimulation Uncovers Functional Network Differences in Healthy Older Adults as Revealed by Resting State EEG Functional Coupling in Brain Network. [PDF]
Resting‐state EEG revealed that older adults with reduced motor cortex excitability display functional connectivity deficits in cognitive and sensorimotor networks and poorer cognitive performance. These findings suggest that motor excitability indexes early neurophysiological vulnerability and highlight EEG as a sensitive tool for detecting subtle ...
Nucci L +9 more
europepmc +2 more sources
Grape ripening heterogeneity in white and red cultivars (Vitis vinifera L.) grown on different calcareous soils using technological and phenolic markers. [PDF]
Abstract BACKGROUND An understanding of grape ripening heterogeneity is essential to optimize vineyard management and to ensure wine quality. This study investigated the effect of calcareous soils with different textures (limestone and marlstone) on the chemical composition of white (‘Grillo’ (GR) and ‘Chardonnay’ (CH)) and red (‘Nero d’Avola’ (ND) and
Vitaggio C +5 more
europepmc +2 more sources
TTV Species Diversity as a Novel Biomarker of Immune Dysregulation in Aging. [PDF]
ABSTRACT Torquetenovirus (TTV) is a prevalent virus whose clinical significance remains unclear, potentially linked to immunosenescence. This study examines TTV species in relation to immune impairment, inflammation, and cellular stress response in aging.
Novazzi F +35 more
europepmc +2 more sources
A Bibliography on the Application of GIS in Archaeology and Cultural Heritage [PDF]
Geographical Information Systems (GIS) applications to archaeological projects of different scales, chronological contexts and cultural milieux has accrued by now a long history and bibliography.
Bogdani, Julian, De_mitri, Eugenio
core +1 more source
Hubstract made for art produced two documentary videos for "Calce viva", exhibition set up during the restoration of the complex and the hemicycle at the "Museum of the Imperial Fora at the Markets of Trajan" in Rome.
Stefano Fiori
doaj +5 more sources
Abandoned Villages in Liguria. Tourist Development and Transformation of the Sense of Place
Liguria is a land rich in coastal villages, for which it is famous all over the world. Still, it has numerous centers scattered inland, perhaps less visible, where the steepness of the hills has allowed the settlement. A subsistence economy characterized
Lucina Napoleone
doaj +1 more source

