Results 141 to 150 of about 2,544,276 (249)

Myelodysplasia From Valproic Acid Resolved by Cessation. [PDF]

Case Rep Hematol
Ugwu C, Palma AU, Bhat R, Taneja A.
europepmc   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Serum carnitine, ?-hydroxybutyrate, and ammonia levels during valproic acid therapy

, 1995
This study was performed in order to determine the effects of valproic acid on serum free carnitine, ?-hydroxybutyrate and blood ammonia. Serum free carnitine, ?-hydroxybutyrate and blood ammonia levels were measured in 24 epileptic children and in 24 ...
Toksoy H.B., Tanzer F.N., Atalay A.
core  

Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α‐synuclein preformed fibrils‐induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

Brain Pathology, EarlyView.
Omics‐driven drug repositioning reveals pyroxamide as a neuroprotective HDAC1 inhibitor in Parkinson's disease models. Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder mainly characterized by the degeneration of dopaminergic neurons originating in the substantia nigra (SN) pars compacta and projecting to other ...
Paz Cartas‐Cejudo, Marina De Miguel, Leire Extramiana, Mercedes Lachén‐Montes, Silvia Romero‐Murillo, Djordje Gveric, Joaquín Fernández‐Irigoyen, Enrique Santamaría   +7 more
wiley   +1 more source

Acute hypothermia induced by valproic acid. [PDF]

Proc (Bayl Univ Med Cent)
Dasara H, Conn B, Shamim S.
europepmc   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

British Journal of Pharmacology, EarlyView.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Valproic acid remodels phosphatidylglycerol homeostasis and epithelial-macrophage crosstalk in inflammatory signaling. [PDF]

iScience
Ďurišová I, Máčajová M, Zriniová I, Fábryová I, Meta M, Bábelová L, Bilčík B, Kvasnička A, Baláž M, Bernátová S, Petrezsélyová S, Filipp D, Hsu YH, Friedecký D, Čavarga I, Balážová M.   +15 more
europepmc   +1 more source

Epigenetic control of cellular plasticity in breast cancer progression

The FEBS Journal, EarlyView.
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey, Elizabeth Podleszanski, William J. Muller   +2 more
wiley   +1 more source

Mechanisms of weight gain associated with valproic acid: a scoping review. [PDF]

Eur Arch Psychiatry Clin Neurosci
Popkova D, Fellendorf F, Vinberg M, Ceylan D, Bukova-Zideluna A, Fleischmann E, Dalkner N, Tmava-Berisha A, Lenger M, Manchia M, Reininghaus E.   +10 more
europepmc   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland, Samuel J. Belfer, Christine K. Fox, Samantha L. Irwin, Rachel Vassar, Ann Oh, Sruthi Ilangovan, Amy A. Gelfand   +7 more
wiley   +1 more source