Results 161 to 170 of about 2,544,276 (249)

Severe Pediatric MOGAD‐Associated ADEM With Persistent Neurological Morbidity and Later‐Onset Epilepsy of Uncertain Etiology: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This report describes a 7‐year‐old boy with MOGAD presenting as severe ADEM with fever, encephalopathy, seizures, markedly elevated intracranial pressure, diffuse multifocal MRI abnormalities, and serum MOG‐IgG positivity. He required intravenous corticosteroids, plasma exchange, IVIG, and tocilizumab, followed by rehabilitation and ...
Desiree‐Anne Ramsaran, Garrett Gianneschi, Janet Elgallab   +2 more
wiley   +1 more source

Therapeutic potential of edaravone and flurbiprofen in valproic acid-induced autism: Targeting oxidative stress and neuroinflammation. [PDF]

IBRO Neurosci Rep
Hejazi A, Hajisoltani R, Farbib M, Sadr H, Mehrabi F, Baluchnejadmojarad T, Mehrabi S.   +6 more
europepmc   +1 more source

Metformin Attenuates Behavioral Deficits and Oxidative Stress in a Preclinical Model of Autism

Developmental Neurobiology, Volume 86, Issue 4, October 2026.
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental condition lacking effective pharmacological treatments. Metformin has emerged as a candidate for drug repurposing in ASD due to its metabolic and neurobiological actions. This study evaluated the in vivo effects of metformin (400 mg/kg, orally) administered from postnatal day 21 to
Madna Costa Freitas, Renê Felipe de Freitas, Iara Kessila Milhome Vasconcelos, Isadora Porto de Andrade, Maria Helena da Silva Pitombeira, David Ribeiro Fontenele, Pedro Otávio de Freitas Alves, Victoria Soares Diógenes, Ana Maria Sampaio Assreuy, Gislei Frota Aragão   +9 more
wiley   +1 more source

Seizure freedom on subtherapeutic levels of valproic acid. [PDF]

J Family Med Prim Care
Basheikh MA.
europepmc   +1 more source

Synthesis and Characterization of Juglone‐Derived cu (II), Mn (II) and Zn (II) Complexes and Investigation of Their Cytotoxic Activities Against Lung and Colon Cancer Cells in Vitro and in Silico

Journal of Applied Toxicology, Volume 46, Issue 10, Page 3465-3477, October 2026.
ABSTRACT Three new Zn (II), Cu (II) and Mn (II) complexes have been synthesized from 5‐hydroxy‐1,4‐naphthoquinone (HNQ). Elemental analysis, magnetic susceptibility, UV–Vis, IR and Mass spectrometry have all been used to explore the structural characterization of these compounds.
Mustafa Öztatlıcı, Turan Birimoğlu, Semih Güler, Rukiye Betül Çolaksel, Mehmet Tahir Husunet, Mehmet Sönmez   +5 more
wiley   +1 more source

A rare pericallosal lipoma presenting with Lennox-Gastaut syndrome and a remarkable response to valproic acid. [PDF]

Epileptic Disord
Rapal RMLL, Chin HL, Nordli D.
europepmc   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, Volume 95, Issue 4, Page 349-357, October 2026.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

Prevalence of Psychotropic Use and Psychotropic Polypharmacy in a Finnish National Cohort of Persons With Intellectual Disabilities

Journal of Intellectual Disability Research, Volume 70, Issue 10, Page 1112-1124, October 2026.
ABSTRACT Background Psychotropic use and psychotropic polypharmacy are common in people with intellectual disabilities, but representative population‐based studies on this topic are scarce. We evaluated the prevalence of psychotropic use and psychotropic polypharmacy in a Finnish nationwide cohort of people with intellectual disabilities aged 0–97 ...
Ville Virtanen, Leena Saastamoinen, Maria Arvio, Hannu T. Vesala, Sonja Miettinen, Antti Teittinen, Anna‐Maija Tolppanen   +6 more
wiley   +1 more source

Association of <i>TPH2</i> polymorphisms with valproic acid efficacy and neurological adverse events in pediatric epilepsy. [PDF]

Front Pharmacol
Zhu J, Wang X, Shen X, Xia H, He Y, Liu Q, Zhang J, Fan X, Li W.   +8 more
europepmc   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source