Results 161 to 170 of about 35,754 (249)

Analysing lithium, quetiapine and valproic acid on social media: an infodemiology study. [PDF]

Int J Bipolar Disord
Chart-Pascual JP, Alvarez-Mon MA, Montero-Torres M, Lara-Abelenda FJ, Marin-Napal J, Rodriguez-Jimenez R, Martínez-Velasco R, Alberdi-Paramo I, Gonzalez-Pinto A, Fernandez-Lazaro CI.   +9 more
europepmc   +1 more source

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei, Atefeh Taghavi, Amir R. Afshari, Farzaneh Davoudi, Elaheh Gheybi, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

Lithium and valproic acid in bipolar disorder: Beyond mood stabilization, the overlooked role of sleep. [PDF]

World J Psychiatry
Kabadayi Sahin E.
europepmc   +1 more source

Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 510-519, August 2026.
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley   +1 more source

Valproic acid reverses macrophage-mediated temozolomide resistance in macrophage-rich gliomas. [PDF]

NPJ Precis Oncol
Ni X, Chen W, Xu P, Yang Y, Chen M, Chen F, Guo C, Zhang J, Qi X, Chen Z.   +9 more
europepmc   +1 more source

Chemical Profiles, Pharmacological Insights, and In Silico Studies of Antidesma montanum Blume: An Experimental and Computer‐Aided Approach

eFood, Volume 7, Issue 4, August 2026.
Antidesma montanum, an edible wild plant, shows notable nutraceutical and pharmacological potential. Methanol extract profiling (GC–MS) identified bioactive metabolites. In vitro, in vivo, and in silico studies demonstrated significant antidiabetic, anthelmintic, anxiolytic, antidepressant, and antidiarrheal activities, supported by strong molecular ...
Naureen Banu, Najmul Alam, Sadia Farid Jhuma, Mohammad Nazmul Islam, Shady A. Alghazali, Md Abdul Awal, Sanjida Islam, Hafsa Siddiqua, Shafinaz Nur, Md. Sohel Rana   +9 more
wiley   +1 more source

Optimization of individualized therapy with oral valproic acid in pediatric patients with epilepsy based on factors influencing blood concentrations. [PDF]

Front Pharmacol
Qin Y, Zhang N, Zhang P, Teng Y, Xia Z, Mao Z, Wang L, Yang Y, Niu W.   +8 more
europepmc   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, Volume 11, Issue 4, Page 1095-1110, August 2026.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

Potential Pharmacokinetic Interaction Between Enteral Nutrition and Valproic Acid. [PDF]

Eur J Case Rep Intern Med
Lara-Gonzalez NG, Díaz-Rengifo IA, Terleira-Fernández AI, Salas-Butrón MR.   +3 more
europepmc   +1 more source