Results 191 to 200 of about 74,623 (302)

Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hypertrophic scars and keloids, types of pathological scars, arise from dysregulated wound healing, marked by abnormal fibroblast activation and excessive extracellular matrix (ECM) deposition. Current treatments have high recurrence rates and side effects, necessitating targeted therapies. Exosomes, extracellular vesicles mediating
Mengke Wu, Jianfeng Zhang, Na Xiong, Yixiao Ma, Lingling Yong, Huaxu Liu, Qin Guo   +6 more
wiley   +1 more source

Massive Valproic Acid Overdose With Confirmed Pharmacobezoar Formation and Neuromuscular Toxicity: A Case Report and Literature Review. [PDF]

Cureus
Alrazooqi MK, Abumuaileq L, Zia S, Kazim S.   +3 more
europepmc   +1 more source

GSK‐3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid

, 2005
W. Jonathan Ryves, Emma Dalton, Adrian J. Harwood, Robin S. B. Williams   +3 more
openalex   +2 more sources

Defining the Intestinal eCBome and Oxylipin Signaling Systems in a TDP‐43 Mouse Model of Frontotemporal Dementia

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
TDP‐43 overexpressing mice, a genetic model of frontotemporal dementia, exhibit dramatic changes in their small intestinal endocannabinoidome members, in terms of both altered concentrations of lipid mediators and expression of some of their receptors (Cnr1, Gpr119, Gpr55, Pparg) and metabolic enzymes (Napepld, Faah). Also, the levels of some oxylipins
Hayatte‐Dounia Mir, Giada Giorgini, Irene Santos‐García, Elizabeth Dumais, Carmen Rodríguez‐Cueto, Eva de Lago, Cristoforo Silvestri, Nicolas Flamand, Javier Fernández‐Ruiz, Vincenzo Di Marzo   +9 more
wiley   +1 more source

Valproic Acid Induces Endothelial-to-Mesenchymal Transition-Like Phenotypic Switching [PDF]

, 2018
Shamini Murugavel, Antoinette Bugyei‐Twum, Pratiek N. Matkar, Husain Al-Mubarak, Hao H Chen, Mohamed Adam, Shubha Jain, Tanya Narang, Rawand Abdin, Mohammad Qadura, Kim A. Connelly, Howard Leong‐Poi, Krishna K. Singh   +12 more
openalex   +1 more source

DNA methyltransferase inhibitors in hematological malignancies and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 433-461, 15 January 2026.
Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger, Guillermo Garcia‐Manero, Robert Zeiser, Michael Lübbert   +3 more
wiley   +1 more source

Developmental Trajectory of Autistic‐Like Behaviors in a Prenatal Valproic Acid Rat Model of Autism [PDF]

Bin Lian, Yihan He, Da Dong, Li Quan, Tingyong Feng, Ming Li   +5 more
openalex   +1 more source

Valproic Acid Inhibits RhoA-Mediated Vascular Smooth Muscle Cell Contraction. [PDF]

J Korean Med Sci
Park JK, Kim SH, Lee H, Hwang YJ, Cho DH.   +4 more
europepmc   +1 more source

Valproic Acid Combined with Zoledronate Enhance γδ T Cell-Mediated Cytotoxicity against Osteosarcoma Cells via the Accumulation of Mevalonate Pathway Intermediates

, 2018
Shengdong Wang, Hengyuan Li, Chenyi Ye, Peng Lin, Binghao Li, Wei Zhang, Lingling Sun, Zhan Wang, Deting Xue, Wangsiyuan Teng, Xingzhi Zhou, Nong Lin, Zhaoming Ye   +12 more
openalex   +1 more source

When Overdose Strikes: Successful Use of Hemodialysis in Valproic Acid Toxicity. [PDF]

Cureus
Zaringhalam S, Dosanjh H, Awan WA, Gower A, Takher J.   +4 more
europepmc   +1 more source