Results 191 to 200 of about 5,054,451 (380)
Effect of valproic acid on pharmacokinetics of active metabolites of cyclophosphamide in mice.
M Goto+4 more
openalex +2 more sources
Intraoperative defect in haemostasis in a child receiving valproic acid [PDF]
John E. Tetzlaff
openalex +1 more source
Medication‐resistant epilepsy is associated with a unique gut microbiota signature
Abstract Objective Dysfunction of the microbiota–gut–brain axis is emerging as a new pathogenic mechanism in epilepsy, potentially impacting on medication response and disease outcome. We investigated the composition of the gut microbiota in a cohort of medication‐resistant (MR) and medication‐sensitive (MS) pediatric patients with epilepsy.
Antonella Riva+14 more
wiley +1 more source
Diurnal variation in pharmacokinetics of valproic acid with unequal dosing intervals.
IKUO JOHNO+6 more
openalex +2 more sources
Reversal of the Adverse Chronic Effects of the Unsaturated Derivative of Valproic Acid—2-n-Propyl-4-Pentenoic Acid—on Ketogenesis and Liver Coenzyme A Metabolism by a Single Injection of Pantothenate, Carnitine, and Acetylcysteine in Developing Mice [PDF]
Jean Holowach Thurston+1 more
openalex +1 more source
Abstract Objective Generalized tonic–clonic seizures (GTCS) are considered to be among the most devastating seizures due to increased health risks. Use of device‐based therapies, such as vagus nerve stimulation (VNS), is common for those resistant to antiseizure medications and important for those in whom resective surgery is not feasible.
Ana Suller Marti+9 more
wiley +1 more source
MBOAT7 encephalopathy: Characterizing the neurology and epileptology
Abstract Objective Biallelic pathogenic MBOAT7 variants are associated with neurodevelopmental disorders, intellectual disability (ID), epilepsy, and neuropsychiatric disorders such as attention‐deficit/hyperactivity disorder and autism spectrum disorders. We aimed to characterize the epilepsy phenotype in a cohort of patients affected by this syndrome.
Sebastian Ortiz De la Rosa+28 more
wiley +1 more source
Abstract Objective This real‐world, retrospective, multicenter study aims to investigate the effectiveness of highly purified cannabidiol (CBD) in a large cohort of patients with epilepsy of genetic etiology due to an identified monogenic cause. Additionally, we examine the potential relationship between specific genetic subgroups and treatment ...
Emanuele Cerulli Irelli+68 more
wiley +1 more source
Combination of asenapine with valproic acid received regulatory approval for acute treatment of schizophrenia and maniac episodes of bipolar disorders.
Ambavaram Vijaya Bhaskar Reddy+2 more
doaj