Results 11 to 20 of about 25,289 (245)

Comparative effects of valsartan plus cilnidipine or hydrochlorothiazide on nocturnal home blood pressure

open access: yesThe Journal of Clinical Hypertension, 2021
We tested our hypothesis that, in hypertensive patients with higher nocturnal home systolic blood pressure (HSBP) at baseline, a valsartan/cilnidipine (80/10 mg) combination would reduce nocturnal HSBP more markedly than a valsartan/hydrochlorothiazide ...
Takeshi Fujiwara   +4 more
doaj   +1 more source

An Insight Into Intestinal Microbiota of Spontaneously Hypertensive Rats After Valsartan Administration

open access: yesDose-Response, 2021
It has been proven a close relationship between intestinal microbiota and hypertension. Valsartan is a widely used ARB antihypertensive drug; so far, the effect of valsartan on intestinal microbiota remains largely unexplored.
Ying-Zi Qi   +5 more
doaj   +1 more source

Role of sacubitril-valsartan in the prevention of atrial fibrillation occurrence in patients with heart failure: A systematic review and meta-analysis of randomized controlled trials.

open access: yesPLoS ONE, 2022
ObjectiveHeart failure (HF) and atrial fibrillation (AF) are often coexisting. They have common risk factors and pathophysiologic mechanisms. Sacubitril/valsartan has shown efficacy and tolerability in patients with HF.
Xuehui Liu   +4 more
doaj   +2 more sources

EFFECT OF SACUBITRIL/VALSARTAN ON NATRIURESIS, DIURESIS AND BLOOD PRESSURE IN HYPERTENSIVE PATIENTS

open access: yesРациональная фармакотерапия в кардиологии, 2017
Aim. To study the effect of sacubitril/valsartan compared with valsartan on natriuresis, diuresis, blood pressure (BP) and the level of biomarkers in hypertensive patients.Material and methods.
Zh. D. Kobalava   +3 more
doaj   +1 more source

Clinical utility of valsartan in the treatment of hypertension in children and adolescents [PDF]

open access: yes, 2011
Rossana Baracco, Gaurav KapurChildren’s Hospital of Michigan/Wayne State University, Detroit, MI, USAAbstract: Valsartan is a potent antagonist of the type 1 angiotensin receptor (AT1).
Gaurav Kapur, Rossana Baracco
core   +1 more source

Combined Angiotensin Receptor–Neprilysin Inhibitors Improve Cardiac and Vascular Function Via Increased NO Bioavailability in Heart Failure

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundThere is a paucity of data about the mechanisms by which sacubitril/valsartan (also known as LCZ696) improves outcomes in patients with heart failure. Specifically, the effects of sacubitril/valsartan on vascular function and NO bioavailability
Rishi K. Trivedi   +7 more
doaj   +1 more source

Dual Angiotensin Receptor and Neprilysin Inhibitor Ameliorates Portal Hypertension in Portal Hypertensive Rats

open access: yesPharmaceutics, 2020
Background: Portal hypertension is characterized by exaggerated activation of the renin-angiotensin-aldosterone axis. Natriuretic peptide system plays a counter-regulatory role, which is modulated by neprilysin.
Shao-Jung Hsu   +6 more
doaj   +1 more source

Sacubitril/Valsartan and Ivabradine Attenuate Left Ventricular Remodelling and Dysfunction in Spontaneously Hypertensive Rats: Different Interactions with the Renin–Angiotensin–Aldosterone System

open access: yesBiomedicines, 2022
This study investigated whether sacubitril/valsartan and ivabradine are able to prevent left ventricular (LV) fibrotic remodelling and dysfunction in a rat experimental model of spontaneous hypertension (spontaneously hypertensive rats, SHRs) and whether
Fedor Simko   +9 more
doaj   +1 more source

Depression associated with valsartan, angiotensin II receptor antagonist; case report and review of the literature

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Severe depression with suicidal ideation associated with the use of the valsartan , an angiotensin receptor antagonist, is reported. The patient, who was unresponsive to antidepressant medication with two different groups, dramatically recovered ...
Numan Konuk, Mustafa Aydın, Ömer Akay
doaj  

Sacubitril/Valsartan Initiation Among Veterans Who Are Renin‐Angiotensin‐Aldosterone System Inhibitor Naïve With Heart Failure and Reduced Ejection Fraction

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Sacubitril/valsartan, a first‐in‐class angiotensin receptor neprilysin inhibitor, received US Food and Drug Administration approval in 2015 for heart failure with reduced ejection fraction (HFrEF).
April F. Mohanty   +14 more
doaj   +1 more source

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