Results 31 to 40 of about 25,289 (245)

Effect of sacubitril/valsartan on the occurrence of cardiac arrhythmias and the risk of sudden cardiac death in heart failure: A meta-analysis of randomized controlled trials

Frontiers in Cardiovascular Medicine, 2022
BackgroundSacubitril/valsartan therapy reduced the risks of death and of hospitalization for heart failure (HF). HF and cardiac arrhythmias have shared physiological mechanisems.
Xue-Hui Liu, Xue-Hui Liu, Guan-Ling Wang, Qiang Xu, Qiang Xu, Lei Zhang, Lei Zhang, Hong-Jun Liu, Hong-Jun Liu   +8 more
doaj   +1 more source

Valsartan-mediated chronotherapy in spontaneously hypertensive rats via targeting clock gene expression in vascular smooth muscle cells

, 2019
Objective: This study was to investigate the underlying mechanisms of valsartan chronotherapy in regulating blood pressure variability. Methods: RT-PCR was used to assay clock genes expression rhythm in the hypothalamus, aortic vessels, and target organs
Xiaotong Zhang (2341759), Yanyun Ding (6709508), Zhangqing Ma (6709517), Xiaoyun Liu (154889), Kui Yang (83118), Deixi Zhou (6709514), Jiajie Luan (6709523), Yaqin Wang (188672), Wen Zhang (7555), Wusan Wang (6709520), Haiju Cui (6709511), Lu Chen (75170)   +11 more
core   +1 more source

Renal outcomes of sacubitril/valsartan compared with valsartan under triple whammy exposure in heart failure patients: A retrospective observational study

Nefrología
Background: The concurrent use of renin–angiotensin–aldosterone system (RAAS) inhibitors, diuretics, and nonsteroidal anti-inflammatory drugs (NSAIDs), known as the “triple whammy (TW),” increases the risk of acute kidney injury (AKI).
Yusuke Nakazawa, Midori Nakamura, Yusuke Kashiwagi, Takashi Kawakubo   +3 more
doaj   +3 more sources

Efficacy and Safety of Valsartan/Hydrochlorothiazide Fixed-Dose Combination Compared with Amlodipine Monotherapy as First-Line Therapy for Mild to Moderate Hypertension

, 2011
This double-blind, active- and randomized-controlled study compared the efficacy and safety of a fixed-dose combination of valsortan/ hydrochlorothiazide 80 mg/12.5 mg once daily ( n = 32) with amlodipine monotherapy 5 mg once daily (n = 33 ) for 8 weeks
趙嘉倫;林彥宏;林隆君;林亮宇;蔡佳醍;王怡智;黃瑞仁;江福田, CHAO, CHIA-LUN;LIN, YEN-HUNG;LIN, LUNG-CHUN;LIN, LIAN-YU;TSAI, CHIA-TI;WANG, YI-CHIH;HWANG, JUEY-JEN;CHIANG, FU-TIEN   +1 more
core   +1 more source

Endothelial function of vessels in patients with chronic kidney disease combined with subclinical hypothyroidism under the influence of combined antihypertensive therapy.

Medičnì Perspektivi, 2018
The aim of the study: to evaluate the endothelial function of the vessels under the influence of combined antihypertensive therapy (valsartan 160 mg / amlodipine 5 mg vs valsartan 160 mg / hydrochlorothiazide 12,5 mg) in patients with CKD and subclinical
I. P. Garmish
doaj   +1 more source

Impact of sacubitril/valsartan on echo parameters in heart failure patients with reduced ejection fraction a prospective evaluation

International Journal of Cardiology: Heart & Vasculature, 2019
Background: Sacubitril/valsartan has been shown to improve mortality and reduce hospitalizations in patients with heart failure (HF) with reduced ejection fraction (HFrEF).
Geoffrey Bayard, Antoine Da Costa, Romain Pierrard, Cécile Roméyer-Bouchard, Jean Baptiste Guichard, Karl Isaaz   +5 more
doaj   +1 more source

Effectiveness of sacubitril-valsartan in patients with cancer therapy-related cardiac dysfunction (CTRCD): a systematic review of clinical and preclinical studies

, 2022
Cancer therapy-related cardiac dysfunction (CTRCD) is a critical problem with an impact on both oncological and cardiovascular prognosis, especially when it prevents patients from receiving cancer treatment.
Neto, Mansueto G, Tse, Gary, Biondi-Zoccai, Giuseppe, Mesquita, Evandro T, Roever, Leonardo, Chan, Jeffrey S, Duraes, Andre R, Liu, Tong, Bitar, Yasmin S, Boochi, Edimar A   +9 more
core   +1 more source

Co-inhibition of Angiotensin II Receptor and Endothelin-1 Attenuates Renal Injury in Unilateral Ureteral Obstructed Mice

Kidney & Blood Pressure Research, 2016
Background/Aims: Both endothelin-1 (ET-1) and the renin-angiotensin system (RAS) may play important roles in renal fibrosis in the obstructed kidney.
Yoon-Kyung Chang, Hyunsu Choi, Jin Young Jeong, Ki-Ryang Na, Kang Wook Lee, Dae Eun Choi   +5 more
doaj   +1 more source

The Effect of Angiotensin Receptor and Neprilysin Inhibitors on Quality of Life in Patients with Heart Failure with Reduced Ejection Fraction and Functional Mitral Regurgitation

Рациональная фармакотерапия в кардиологии, 2023
Aim. To compare the change in quality of life indicators and the main clinical and instrumental parameters in patients with chronic heart failure (CHF) and functional mitral regurgitation (FMR) under the influence of sacubitril/valsartan compared with ...
A. S. Ryazanov, E. V. Shikh, O. V. Kechina, M. V. Makarovskaya, A. A. Kudryavtsev   +4 more
doaj   +1 more source

Inhibitory Effect of Valsartan on Pterygium Fibroblasts [PDF]

, 2020
Purpose: Angiotensin receptor blockers (ARBs) were shown to have antifibrotic properties in ocular and systemic diseases. In this study, our aim was to investigate the effect of an angiotensin receptor blocker, valsartan, on pterygium fibroblasts and ...
Kucuk, Erkut, Erkut Küçük, Işıl Aydemir, Oktay Özkan, Zor, Kursad Ramazan, Aydemir, Isil, Ozkan, Oktay, Kürsad Ramazan Zor   +7 more
core   +1 more source