Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Domestic Value Added and Employment Generated by Chinese Exports: A Quantitative Estimation [PDF]
We develop an input-output methodology to estimate how Chinese exports affect the country’s total domestic value added (DVA) and employment for 1995 and 2002.
Sung, YunWing +8 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
An Analysis of the 2002 Farm Bill’s Value-Added Producer Grants Program [PDF]
Our objective is to identify the determinants for success among USDA’s Value- Added Producer Grants (VAPG) program recipients. Business development has become an important program in departments of agricultural economics.
Boland, Michael A. +2 more
core
Rights-based approaches to development: what is the value-added?
, 2008 Advocates and activists for human rights are currently facing a paradox: the coexistence of profound challenges in familiar territory (civil liberties) alongside expansion into new areas.
Gready, Paul
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Demographic Factors Affecting the Adoption of Multiple Value-Added Practices by Oklahoma Cow-Calf Producers [PDF]
The utilization of marketing programs to enhance feeder calf value has been met with modest success in Oklahoma. Value-added programs are continually promoted as avenues for improving cow-calf profitability, but producer adoption of value-added practices
Raper, Kellie Curry +6 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Active Governance: the value added by community involvement in governance [PDF]
, 2017 This is the final version of the article. Available from the Joseph Rowntree Foundation via the URL in this record.Wider community engagement in governance is frequently argued, across the political parties, to be vital to improving public services and ...
Maguire, K, Truscott, F
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source