Results 101 to 110 of about 9,110,558 (300)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Value Added Taxes, Chain Effects and Informality [PDF]

This paper investigates determinants of informal economic activity. We present an equilibrium model of informality and test its implications using a survey of 48,000+ small firms in Brazil.
Jose A. Scheinkman, Aureo de Paula
core  

Non-destructive real-time monitoring of underground root development with distributed fiber optic sensing

Plant Methods
Crop genetic engineering for better root systems can offer practical solutions for food security and carbon sequestration; however, soil layers prevent the direct visualization of plant roots, thus posing a challenge to effective phenotyping.
Mika Tei, Fumiyuki Soma, Ettore Barbieri, Yusaku Uga, Yosuke Kawahito   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Updating “BePLi Dataset v1: Beach Plastic Litter Dataset version 1, for instance segmentation of beach plastic litter” with 13 object classesSeanoe

Data in Brief
Beaches are recognized as major sinks of plastic litter and key sites where litter fragments into countless small pieces. Because those fine particles are almost impossible to remove from the natural environment, it is essential to monitor macroplastic ...
Mitsuko Hidaka, Koshiro Murakami, Shintaro Kawahara, Yujin Nakagawa, Daisuke Sugiyama, Shin’ichiro Kako, Daisuke Matsuoka   +6 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Lignin‐derived hard carbon anode with a robust solid electrolyte interphase for boosted sodium storage performance

Carbon Energy
Hard carbon is regarded as a promising anode candidate for sodium‐ion batteries due to its low cost, relatively low working voltage, and satisfactory specific capacity.
Jingqiang Zheng, Yulun Wu, Chaohong Guan, Danjun Wang, Yanqing Lai, Jie Li, Fuhua Yang, Simin Li, Zhian Zhang   +8 more
doaj   +1 more source

From phenotype to mechanism: background-dependent function of CtDnaJ.16 in thermotolerance-divergent Coriolopsis trogii haploids

Frontiers in Microbiology
The two haploids, Ct001_29 and Ct001_31, derived from the thermotolerant strain Coriolopsis trogii Ct001, differ in mating type and exhibit distinct thermotolerance capacities.
Lining Wang, Chaoxue Ma, Siyu Zhao, Jinjing Li, Jinjing Li, Lingjie Zhou, Lingjie Zhou, Laixin Dai, Biao Hu, Nianfang Ma, Qingfu Wang, Zhihai Huang   +11 more
doaj   +1 more source

Value-adding enterprise [PDF]

Nature, 2010
openaire   +2 more sources