Results 81 to 90 of about 9,110,558 (300)
NanomaterialsAtomically dispersed metal–nitrogen–carbon (M-N-C) catalysts are regarded as ideal catalytic materials for the oxygen reduction reaction (ORR) under alkaline conditions.
Jian Chen +7 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Is the Value Added Tax Naturally Progressive? [PDF]
A broad based consumption tax, such as a value added tax, is generally considered to be a regressive tax. This conclusion, however, has not taken into account the fact that in developing countries the commodities on which poor households spend most of ...
Hatice Jenkins +2 more
core
Discover Applied SciencesBiosurfactants (BS) are highly emulsifying, biodegradable, non- or low-toxic, stable and multifunctional molecules. However, high production costs and low yields limit their large-scale production and use.
Yapi Joel Angba +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Group recognition as a new design methodology for selective hydrogenation
Green CarbonSelective hydrogenation is a core reaction in heterogeneous catalysis and is employed in over one-quarter of industrial chemical processes involving fine chemicals, pharmaceuticals, and energy conversion. However, achieving selectivity in multifunctional
Minghang Li +3 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Student Sorting and Bias in Value Added Estimation: Selection on Observables and Unobservables [PDF]
Non-random assignment of students to teachers can bias value added estimates of teachers’ causal effects. Rothstein (2008) shows that typical value added models indicate large counter-factual effects of 5th grade teachers on students’ 4th grade learning,
Jesse Rothstein
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source