Results 161 to 170 of about 3,030,006 (223)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Dependent conditional value-at-risk for aggregate risk models. [PDF]

Heliyon, 2021
Josaphat BP, Syuhada K.
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Pan-Immune-Inflammatory value and risk of latent tuberculosis infection. [PDF]

Sci Rep
Ye X, Kang X, Zhang H, Wang W.
europepmc   +1 more source

How to promote the healthy development of continuous participation in smart medical and elderly care systems: The dual perspective of perceived value and risk. [PDF]

Digit Health, 2023
Cao C, Dai H, Li D.
europepmc   +1 more source

The predictive value of risk assessment models for venous thromboembolism on gynaecological cancer patients. [PDF]

J Coll Med S Afr
Ratshabedi PK, Chikandiwa A, Mbodi L.
europepmc   +1 more source

Analysis of the Influence of Serum MMP-2 and vWF Levels on the Predictive Value of Risk Grade and Prognosis of Patients with Acute Myeloid Leukemia. [PDF]

Contrast Media Mol Imaging, 2022
Liu M, Liu M, Yang Q, Zhang L.
europepmc   +1 more source

Left ventricular global longitudinal strain adds incremental value for risk prediction in unselected clinical patients. [PDF]

Eur Heart J Imaging Methods Pract
Backhaus SJ, Treiber JM, Wolter JS, Kriechbaum SD, Saamann D, Schuster A, Sossalla S, Rolf A.   +7 more
europepmc   +1 more source

Associations With Extubation Failure and Predictive Value of Risk Analytics Algorithms With Extubation Readiness Tests Following Congenital Cardiac Surgery. [PDF]

Pediatr Crit Care Med, 2022
Hames DL, Sleeper LA, Bullock KJ, Feins EN, Mills KI, Laussen PC, Salvin JW.   +6 more
europepmc   +1 more source