Results 91 to 100 of about 34,041,313 (284)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Authentic leadership for value-based healthcare

open access: yes
This chapter describes the importance of leadership in implementing value-based healthcare through authentic leadership principles. It discusses definitions, contemporary literature on the topic, and the change management implications that need to be ...
Silvester, Tracey, Olley, Richard
core  

Best Practices in Incentive Compensation from the Perspective of Value-based Management [PDF]

open access: yes
As a consequence of the recent global financial crisis, the current economic environment emphasized the weak correlation between company performance and the incentives received by the management staff.
Costin Ciora, Eduard Mădălin Dinu
core  

Measuring project performance with value-based methods

open access: yesBusiness: Theory and Practice, 2008
The value of the company is the benefit of positive net present value projects which give better return than the cost of invested capital. It is important for investors and shareholders to choose the optimal collection of strategic decisions and evaluate
Tomas Petravičius
doaj  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Increasing the value of quality management systems

open access: yes, 2019
Over one million organisations have a Quality Management System (QMS) certified to the ISO9000 standard; however, the system requires a lot of resources and its value has been questioned. The purpose of this paper is to investigate how different types of
Elg, Mattias,   +3 more
core  

Repository Strategic Management Business Journal

open access: yes
Strategic Management Business Journal is a forum for researchers in management science, especially in creating the effect of improving organizational performance in human resource management, financial management, and marketing management.
journal, strategic management business
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Value-Based Inventory Management [PDF]

open access: yes
The basic financial purpose of a firm is to maximize its value. An inventory management system should also contribute to realization of this basic aim.
Michalski, Grzegorz
core  

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