Results 151 to 160 of about 20,820,978 (349)

Prognostic value of morphometry in breast cancer. [PDF]

open access: bronze, 1991
J. P. A. Baak   +2 more
openalex   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Economic Evaluation of Ready-to-Dilute Thiotepa (Tepylute®): Institutional Cost Offsets and Time Savings Compared to Lyophilized Thiotepa in a United States Hospital Pharmacy

open access: yesClinicoEconomics and Outcomes Research
Orlaith Ryan,1 Maurice Clancy,1 Alanna MacDonald,2 Laura Pastor,2 Megan Bourque2 1Shorla Oncology, Clonmel, Co., Tipperary, Ireland; 2Value and Evidence Department, EVERSANA, Burlington, ON, CanadaCorrespondence: Orlaith Ryan, Shorla Oncology, Questum ...
Ryan O   +4 more
doaj  

Fluorination of Silver Phosphate in Nickel Reaction Vessels for Triple Oxygen Isotope Analysis. [PDF]

open access: yesRapid Commun Mass Spectrom
Wostbrock JAG   +4 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Value assignment of Reference Material 8405 hazelnut flour for allergen detection

open access: gold, 2022
Melissa Phillips   +3 more
openalex   +1 more source

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