Results 231 to 240 of about 20,820,978 (349)

Values and Value

This dissertation examines how moral value is constructed, performed, and rendered exchangeable on a market for Diversity, Equity, and Inclusion (DEI) consulting in Denmark. While DEI work is often framed as a morally driven effort to improve organizational life, the growing importance of external actors influencing organizational DEI agendas raises ...
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Patient perspectives on cost and quality measures in value-based cancer care. [PDF]

Health Aff Sch
Balch A, Lahm M, Brunisholz KD, Morrow C, Brittle C, Genin RB, Falope O, Valuck T.   +7 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Correction: Divergent effects of environmental concern and risk perception on pro-environmental intention: an international study across 17 countries. [PDF]

Sci Rep
Kikko Y, Ishigaki T.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A holistic approach for quantifying the value of public health programs: social return on investment (SROI) analysis of a mobile clinic as an example. [PDF]

Front Public Health
Kumar S, Mallett A, Olsen S, Coleman A.
europepmc   +1 more source

Expanded Relative Operator Entropies and Operator Valued α-Divergence

, 2015
Masatoshi Ito Hiroshi Isa, Eizaburo Kamei, Masayuki Watanabe   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Analysis of fossil fuel consumption and socioeconomic drivers of respiratory disease mortality in G7 countries: an ARDL and VAR model approach. [PDF]

Cad Saude Publica
Martins T, Arenhart RS, Reichert B, Jacobi LF, Souza AM.   +4 more
europepmc   +1 more source