Yarrowia lipolytica as a potential chassis for value-added products using a co-culture system and lignocellulose biomass-derived xylose. [PDF]
Naz T +6 more
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
System Design in CO<sub>2</sub> Electrolysis: Integrating Value-Added Anode Reactions with Cathodic Reduction. [PDF]
Zhai Y, Wang C, Chen Z.
europepmc +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Nutritional Value of Brewer's Spent Grain and Consumer Acceptance of Its Value-Added Food Products. [PDF]
Eche V, Emenike CU, Rupasinghe HPV.
europepmc +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Developing high-value-added cotton via rebuilding astaxanthin biosynthesis pathway. [PDF]
Miao L +8 more
europepmc +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Up-recycling of waste wood into value-added room temperature phosphorescent materials. [PDF]
Yin WM +9 more
europepmc +1 more source

