Results 41 to 50 of about 476,055 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Digital Innovation Through Behavioural Analytics: Evidence from Acquisition Channels and Engagement in Global Cruise Firms

open access: yesInformation
Digital transformation has reshaped how cruise firms acquire, engage and retain customers. However, existing research rarely integrates these behavioural dimensions within a unified analytical framework.
Dimitrios P. Reklitis   +6 more
doaj   +1 more source

Tourism Global Value Chains and Africa

open access: yes, 2017
As Africa continues to attract record numbers of international arrivals, there are industry undercurrents that influence the continent’s participation in tourism value chains.
Daly, Jack   +5 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Behavioral Economics in EU: Meat, ESG, Macroeconomics

open access: yesEconomies
This study examines the impact of macroeconomic and ESG (Environmental, Social, and Governance) factors on meat consumption in EU countries through a behavioral economics framework.
Panagiotis Karountzos   +3 more
doaj   +1 more source

Economic benefits of Northeast Asia energy interconnection: A quantitative analysis based on a computable general equilibrium model

open access: yesGlobal Energy Interconnection, 2021
There has been an intense discussion on the energy infrastructure cooperation in Northeast Asia. Most studies have focused on the technical feasibility of grid interconnection, deployment of renewable energy, and have ignored the quantitative analysis of
Jian Wang, Shenghao Feng, Junyong Xiang
doaj   +1 more source

When value chains go south: governance and upgrading of the Kenyan leather sector

open access: yes, 2018
In the last three decades, the global economy has witnessed an ambivalent phenomenon of integration through disintegration. Whilst the amount of regional and global trade dramatically increased, vertical specialisation prompted the outsourcing of ...
Pasquali, Giovanni
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The role of trust and networks in developing Nicaraguan farmers’ agribusiness capacities

open access: yesJournal of Agriculture and Rural Development in the Tropics and Subtropics, 2018
The main focus of most programmes in developing countries carried out by NGOs is to develop small-scale farmers’ capacities. One approach hereby is to use multi-stakeholder innovation systems, such as the ‘Nicaraguan Learning Alliance’ (NLA).
Dirk Hauke Landmann   +1 more
doaj  

An inter-city input-output database distinguishing firm ownership in the Greater China area during 2002–2017

open access: yesScientific Data
Most multi-region input-output (MRIO) tables in China focus on provinces or urban agglomerations and ignore the tremendous geographical heterogeneities of economic activities across Chinese prefectural cities, where regional economic centres are usually ...
Yafei Wang   +16 more
doaj   +1 more source

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