Results 51 to 60 of about 6,506,591 (256)

Small business, big footprint: the digital carbon footprint dilemma in small and medium-sized enterprises

International Journal of Information Systems and Project Management
A major contributor to climate change is the emissions from Information and Communication Technology (ICT) devices and digitalisation. Energy use, heat production, and the operation of assets all contribute to the production of harmful emissions ...
Ágnes Sándor, Ákos Gubán
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Diversification of Rice-Based Cropping Systems with Vegetables and Legumes in Asia and Africa

Crops
Rice is one of the most important staple foods worldwide. Asia, particularly South and Southeast Asia, is a major rice producer, and rice production is also gradually increasing in Africa.
Ramasamy Srinivasan
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Break the chains : a manifesto for the Break the Chains conference to be held on August 8-10, 2003, University of Oregon, Eugene, OR.

, 2003
A manifesto for the conference that was a collaborative effort between the Break the Chains Collective (Eugene, OR), the Anarchist Prisoner's Legal Aid Network (AKA APLAN, Portland, Or) and the National Anarchist Black Cross Network, stating that the ...
Break the Chains (Organization)
core   +1 more source

Harnessing Digital Marketing Analytics for Knowledge-Driven Digital Transformation in the Hospitality Industry

Information
In the digitally saturated hospitality environment, research on digital transformation remains dominated by macro-level adoption trends and user-generated content, while the potential of micro-level web-behavioural data remains largely untapped.
Dimitrios P. Reklitis, Marina C. Terzi, Damianos P. Sakas, Panagiotis Reklitis   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Global value chains and income inequality in Africa

Recent technological advances and policy initiatives present Africa with enormous growth potential from participating in global value chains (GVCs). However, the widening income inequality is raising questions as to whether participation in GVCs plays ...
Ali, Williams, Mumin, Yazeed Abdul
core   +1 more source

Global Value Chains, Development and Emerging Economies

, 2015
In recent decades, profound changes in the structure of the global economy have reshaped global production and trade and have altered the organization of industries and national economies into global value chains (GVCs).
Gereffi, G
core   +1 more source