Results 71 to 80 of about 476,055 (308)
Knowledge flows and global value chains [PDF]
, 2022 The organisation of global value chains via supplier links and within business groups shapes global trade and forms a major channel through which knowledge is disseminated between countries. Global value chains are also an important channel through which
Bisztray, Márta +2 more
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Trade crisis and recovery : restructuring of global value chains [PDF]
The recent large and rapid slowdown in economic activity has resulted in even larger and more rapid declines in international trade. As world trade is set to rebound, this paper addresses three questions: (i) Will trade volumes rebound in a symmetric ...
Winkler, Deborah, Milberg, William
core
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Simulation of Tourism Supply Chain Planning with Digital Marketing Demand Forecasts
InformationTourism supply chains have become increasingly vulnerable to demand volatility amid disruption and recovery, creating a need for forecasting inputs that are both timely and operationally meaningful.
Dimitrios P. Reklitis +4 more
doaj +1 more source
Dynamic Capabilities of Global Value Chains: From Selection to Deployment
, 2023 Participation in global value chains (GVCs) has become an increasingly necessary and (potentially) lucrative endeavour for organisations operating in today’s markets. As the 2020 pandemic shows, this endeavour is not of a trivial nature.
Mistry, A, Arndt, F, Katic, M, Nafei, S
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The role of standards in global value chains [PDF]
Standards have become an increasingly important dimension in global trade. Without the capacity to meet the growing body of standards, producers may either have difficulty in entering global markets, or be relegated to unprofitable and low-margin niches.
Kaplinsky, Raphael
core
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Value Added Trade Restrictiveness Indexes. Measuring Protection within Global Value Chains [PDF]
, 2018 Production and trade are increasingly organized within Global Value Chains (GVCs) and therefore assessing who effectively pays the cost of protection is not straightforward.
Luca Salvatici +2 more
core +1 more source