Results 61 to 70 of about 476,055 (308)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Harnessing Digital Marketing Analytics for Knowledge-Driven Digital Transformation in the Hospitality Industry

Information
In the digitally saturated hospitality environment, research on digital transformation remains dominated by macro-level adoption trends and user-generated content, while the potential of micro-level web-behavioural data remains largely untapped.
Dimitrios P. Reklitis, Marina C. Terzi, Damianos P. Sakas, Panagiotis Reklitis   +3 more
doaj   +1 more source

Global value chains and income inequality in Africa

Recent technological advances and policy initiatives present Africa with enormous growth potential from participating in global value chains (GVCs). However, the widening income inequality is raising questions as to whether participation in GVCs plays ...
Ali, Williams, Mumin, Yazeed Abdul
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Agroeconomic Indexes and Big Data: Digital Marketing Analytics Implications for Enhanced Decision Making with Artificial Intelligence-Based Modeling

Information
Agriculture firms face an array of struggles, most of which are financial; thus, the role of decision making is discerned as highly important. The agroeconomic indexes (AEIs) of Agriculture Employment Rate (AER), Chemical Product Price Index (CPPI), Farm
Nikolaos T. Giannakopoulos, Marina C. Terzi, Damianos P. Sakas, Nikos Kanellos, Kanellos S. Toudas, Stavros P. Migkos   +5 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Global value chains are not always global: The 'global factory'and 'exo-net'value architectures

, 2021
Reinterpreting and Reimagining Megatrends in the World Economy Renu Agarwal, ... 'Global value chains are not always global – The 'global factory'and ..
Brian Wixted, Wixted, B, Bliemel, M, Martin Bliemel   +3 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Evaluating Digital Marketing, Innovation, and Entrepreneurial Impact in AI-Built vs. Professionally Developed DeFi Websites

Future Internet
This study evaluates whether an AI-built DeFi website case can match professionally developed DeFi platforms in digital marketing performance, innovation-related strategic behavior, and entrepreneurial impact. Using a multi-method design, we compare five
Nikolaos T. Giannakopoulos, Damianos P. Sakas, Nikos Kanellos   +2 more
doaj   +1 more source

From farm to market: Impacts of climate shocks on selected agricultural value chains in Ethiopia

While many of the studies to date have focused on the production end of the value chain-i.e., ways to help farmers grow more food, there is limited evidence regarding the impacts of climate shocks on the other stages of agricultural value chains ...
Yitbarek, Eleni, Tesfaye, Wondimagegn
core   +1 more source