Results 141 to 150 of about 1,015,089 (357)

Value creation logics: a UK case study

, 2015
Value creation is the core purpose of organisations, and the Value Creation Logics (VCLs) describe how organisations create value for their customers through the provision of goods or services.
Pan, Yu-Chun, Jackson, Paul, Limburg, Diana   +2 more
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Macro-Social Marketing and the Complexity of Value Co-Creation

, 2019
Complexity is an inherent hallmark of macro-social marketing with its remit of doing social good, changing behaviours, and improving the quality of our lives.
McHugh, P, Christine Domegan, Patricia McHugh, Domegan, C   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Customer-to-customer co-creation of value in the context of festivals.

The notion of customers co-creating value with the firm has recently gained considerable attention within the service marketing discipline. The Service-Dominant (S-D) and the Customer-Dominant (C-D) logic in marketing in particular emphasise the active ...
Rihova, I
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Exploring co-creation networks : creating balanced centricity within a public transport service

, 2011
This presentation looks at exploring co-creation networks and creating balanced centricity within a public transport ...
Jaakkola, Elina, Alexander, Matthew
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Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Contextualising co-creation of value in electronic personal health records

, 2014
This conceptual paper is a preliminary part of an ongoing study into take-up of electronic personal health records (ePHRs). The purpose of this work is to contextually ‘operationalise' Grönroos’ (2012) model of value co-creation in service for ePHRs ...
Lynda Andrews, Randike Gajanayake, Gajanayake, Randike, Sahama, Tony R., Andrews, Lynda, Tony Sahama   +5 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Spontaneity vs. suppression: Differential impacts of platform types on user value co-creation behavior in online brand communities

Acta Psychologica
User participation in value co-creation is a crucial guarantee for the successful operation of online brand communities. Based on the Cognition-Affect-Conation (C-A-C) theoretical framework, this study constructs a theoretical model of the influencing ...
Chengyi Le, Zixin Wang, Jingya Wang, Ting Lu   +3 more
doaj   +1 more source

The co-evolution of organizational value capture, value creation and sustainable advantage

Despite recent emphasis on intra-organizational issues, scholarship on organizations, management and strategy remains unduly reliant on economic models, such as the industrial organization (IO) market structure-based analysis. The focus of such models is
Pitelis, Christos
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