Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
The value co-creation mechanism of Public Cultural Services ecosystem in China based on "public value" theory. [PDF]
Li X, Lam JFI, Lin Z, Song K.
europepmc +1 more source
Value co-creation with family caregivers to people with dementia through a tailor-made mHealth application: a qualitative study. [PDF]
Kagwa AS, Konradsen H, Kabir ZN.
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Digital age: The path choice of government-citizen value co-creation. [PDF]
Guo J, Zhang H.
europepmc +1 more source
The Influence of Tourists' Online Value Co-creation Behavior on Consumer-Brand Relationship Quality: The Moderating Effect of Altruism. [PDF]
Zhang Y, Liu Y, Tao W.
europepmc +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A social cognitive theory of customer value co-creation behavior: evidence from healthcare. [PDF]
Hasan MM +4 more
europepmc +1 more source

